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Atezolizumab
Bevacizumab
Dexamethasone
Capecitabine
PF-06863135
TAR-210
Pembrolizumab
KRT-232
Pertuzumab
Tisotumab

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Active trials

11 of 17 total trials

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

The purpose of the study is to evaluate the overall survival of participants treated with imetelstat compared to best available therapy with intermed...

Enrolling
Myelofibrosis
Drug: Imetelstat
Drug: Best Available Therapy (BAT)

The purpose of this study is to evaluate if milvexian is at least as effective as apixaban for reducing the risk of the composite stroke and non-cent...

Active, not recruiting
Atrial Fibrillation
Drug: Apixaban Placebo
Drug: Milvexian

The main purpose of this study is to compare the disease-free survival between participants receiving treatment with TAR-210 versus investigator's ch...

Enrolling
Non-Muscle Invasive Bladder Cancer
Drug: Gemcitabine
Drug: MMC

A study to learn about a new medicine called ARV-471 (PF-07850327) in people who have advanced metastatic breast cancer.

Active, not recruiting
Advanced Breast Cancer
Drug: ARV-471
Drug: Fulvestrant
Locations recently updated

The purpose of this clinical trial is to (1) learn whether the BCMA-CD3 bispecific antibody elranatamab can provide more benefit to people with multi...

Enrolling
Multiple Myeloma
Drug: Elranatamab
Drug: Pomalidomide

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer bene...

Enrolling
Post-Polycythemia Vera MF (Post-PV-MF)
Primary Myelofibrosis (PMF)
Drug: Best Available Therapy (BAT)
Drug: KRT-232

GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as mainte...

Enrolling
Peritoneal Cancer
Fallopian Tube Cancer
Drug: Bevacizumab
Drug: Mirvetuximab soravtansine plus Bevacizumab

Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemo...

Active, not recruiting
Ovarian Neoplasms
Fallopian Tube Adenocarcinoma
Drug: Paclitaxel
Biological: Placebo

This is an open-label, multinational, randomized Phase 2 study confirming the clinical benefit of 20 mg futibatinib and evaluating the safety and eff...

Enrolling
FGFR2 Fusions
Advanced Cholangiocarcinoma
Drug: TAS-120

The safety and efficacy of pembrolizumab plus the investigator's choice of chemotherapy will be assessed compared to placebo plus the investigator's...

Active, not recruiting
Breast Neoplasms
Drug: dextrose
Drug: liposomal doxorubicin

This trial is being done to find out whether tisotumab vedotin works better than chemotherapy to treat cervical cancer. People in this study have cer...

Active, not recruiting
Cervical Cancer
Drug: topotecan
Drug: gemcitabine

Trial sponsors

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