Sarasota Memorial Hospital | Clinical Research Center

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1540 S. Tamiami Trail, STE 302, Sarasota, Florida, United States of America

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Active trials

23 of 125 total trials

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

The purpose of this study is to evaluate whether milvexian compared to placebo reduce the risk of recurrent ischemic stroke.

Ischemic Stroke; Ischemic Attack, Transient
Drug: Placebo
Drug: Milvexian

This Phase 3 study is designed to compare the efficacy and safety of mirvetuximab soravtansine vs. investigator's choice chemotherapy in patients wit...

Active, not recruiting
Epithelial Ovarian Cancer
Peritoneal Cancer
Drug: Paclitaxel
Drug: Pegylated liposomal doxorubicin

The purpose of this study is to compare event-free survival (EFS) in participants with Bacillus Calmette-Guerin (BCG)-naive high-risk non-muscle inva...

Bladder Cancer
Biological: Cetrelimab
Biological: BCG Vesiculture

The purpose of this study is to demonstrate safety and effectiveness of the Biosense Webster (BWI) ablation system (THERMOCOOL SMARTTOUCH surround fl...

Drug Refractory Paroxysmal Atrial Fibrillation
Device: TRUPULSE Generator
Device: THERMOCOOL STSF Bi- Directional Navigation Catheter

This is a Phase 2 study to evaluate the clinical activity and safety of ZN-c3 (azenosertib) in adult women with recurrent or persistent uterine serou...

Uterine Serous Carcinoma
Drug: ZN-c3

The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valv...

Atrial Fibrillation
Drug: Non-Vitamin K Oral Antagonists
Device: Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder)

The purpose of this study is to establish the safety and effectiveness of the WATCHMAN™ Left Atrial Appendage Closure (LAAC) Device, including the po...

Active, not recruiting
Drug: Single Antiplatelet Therapy or No Therapy (Control)
Device: WATCHMAN LAAC Device Implant

Prospective, non-randomized, multi-center, international study designed to evaluate the safety and effectiveness of the Aveir™ Dual-Chamber (DR) Lead...

Active, not recruiting
Cardiac Rhythm Disorder
Device: Aveir DR Leadless Pacemaker System

The purpose of the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgi...

Active, not recruiting
Mitral Valve Regurgitation
Mitral Regurgitation
Device: MitraClip System

This study is a prospective, multicenter, randomized controlled trial of an interventional strategy using the ClotTriever System to achieve and maint...

Venous Thromboembolism
Deep Venous Thrombosis
Device: ClotTriever System
Drug: Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc.

The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Exc...

Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
Abdominal Aortic Aneurysm
Device: Gore Excluder or Gore/ Excluder Conformable AAA Endoprosthesis
Device: Medtronic Endurant II or Endurant IIs Stent Graft System

This study will monitor the safety and valve performance of the Edwards CENTERA Transcatheter Heart Valve (THV) System in patients with symptomatic,...

Active, not recruiting
Aortic Valve Stenosis

Inappropriate Sinus Tachycardia (IST) is a prevalent and debilitating condition in otherwise healthy younger patients, resulting in significant loss...

Inappropriate Sinus Tachycardia
Device: AtriCure ISOLATOR Synergy Surgical Ablation System

The primary objective of this study is to collect real-world data on WATCHMAN FLX™ Pro Left Atrial Appendage Closure (LAAC) Device in patients with n...

Atrial Fibrillation
Device: WATCHMAN FLX Pro LAAC Device

This trial is a prospective, randomized, multicenter, multinational, blinded, superiority trial. The objective of this trial is to evaluate the effec...

Ischemic Stroke
Systemic Embolism
Device: AtriClip LAA Exclusion System

The primary objective of this study is to collect sensor data from insertable cardiac monitor systems.

Active, not recruiting
Heart Failure
Device: Investigational LUX-Dx ICM Implant

To evaluate the efficacy and safety of the CryoBalloon Focal Ablation System for the treatment of previously-untreated ("treatment naïve") Barrett's...

Active, not recruiting
Barrett Esophagus
Device: CryoBalloon Ablation System

The objective of this study is to establish the safety and effectiveness of a dual epicardial and endocardial ablation procedure for patients present...

Active, not recruiting
Atrial Fibrillation
Persistent or Longstanding Persistent Atrial Fibrillation
Device: AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation

The purpose of this study is to establish the safety and effectiveness of pulsed field ablation as a first-line ablation treatment for subjects with...

Persistent Atrial Fibrillation
Device: FARAPULSE™ Pulsed Field Ablation (PFA) System
Drug: Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, and Dofetilide

Multicenter, Prospective, Randomized Controlled, Blinded Trial, with a Non-implant Control group; 1:1 randomization.

Active, not recruiting
Heart Failure
Device: IASD System II implant
Other: intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE)

Trial sponsors

National Cancer Institute (NCI) logo
Abbott logo
Boston Scientific logo
AtriCure logo
Gilead Sciences logo
Inari Medical logo
Alexion Pharmaceuticals logo

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