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Southern Specialty Research | Flowood, MS

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Mitapivat
AG-348
Crovalimab
Concizumab

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Active trials

2 of 3 total trials

A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)

This clinical trial is a Phase 2/3 study that will determine the recommended dose of mitapivat and evaluate the efficacy and safety of mitapivat in s...

Active, not recruiting
Sickle Cell Disease
Other: Mitapivat-matching placebo
Drug: Mitapivat

This study is designed to evaluate the efficacy, safety and pharmacokinetics of crovalimab compared with placebo as adjunct therapy in the prevention...

Active, not recruiting
Sickle Cell Disease
Drug: Crovalimab
Drug: Placebo

Trial sponsors

Agios Pharmaceuticals logo
Novo Nordisk logo
Roche logo

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