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Mitapivat
Crizanlizumab
AG-348
Crovalimab
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Wendy Thomson
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Active trials
3 of 4 total trials
This clinical trial is a Phase 2/3 study that will determine the recommended dose of mitapivat and evaluate the efficacy and safety of mitapivat in s...
Active, not recruiting
Sickle Cell Disease
Other: Mitapivat-matching placebo
Drug: Mitapivat
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This study is designed to evaluate the efficacy, safety and pharmacokinetics of crovalimab compared with placebo as adjunct therapy in the prevention...
Active, not recruiting
Sickle Cell Disease
Drug: Crovalimab
Drug: Placebo
A phase III, multi-center, randomized, placebo-controlled, double-blind study to assess efficacy and safety of crizanlizumab (5 mg/kg) versus placebo...
Enrolling
Sickle Cell Disease
Biological: Crizanlizumab
Drug: Placebo
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