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St. Boniface Hospital | Cardiology Research

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Active trials

10 of 90 total trials
Locations recently updated

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation (HERMES)

This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will either get z...

Enrolling
Heart Failure
Drug: Placebo
Drug: Ziltivekimab

The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivek...

Enrolling
Acute Myocardial Infarction (AMI)
Cardiovascular Risk
Drug: Ziltivekimab
Drug: Placebo

The purpose of this study is to assess if using the Impella® CP (or Impella® 2.5) device during high-risk PCI in patients with reduced left-sided hea...

Active, not recruiting
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump

This study will evaluate the efficacy of TNX-103 (oral levosimendan) compared with placebo in subjects with PH-HFpEF as measured by the change in 6-M...

Enrolling
Pulmonary Hypertension
Drug: TNX-103
Drug: Placebo

This study is a randomized, double-blind, multicenter, placebo-controlled trial to evaluate the safety and efficacy of a novel therapeutic agent, Nov...

Enrolling
Covid19
Biological: Placebo
Biological: Novaferon

This clinical trial will study the effects of aficamten (versus placebo) on the quality of life, exercise capacity, and clinical outcomes of patients...

Active, not recruiting
Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Drug: Aficamten
Drug: Placebo

This is a Phase 2 adaptive, double-blinded, placebo-controlled, randomized, multi-center trial study to evaluate the safety and efficacy of a single...

Active, not recruiting
Congestive Heart Failure
Drug: AB-1002

This is a Canadian multicenter randomized controlled trial to assess remote patient management. Patients will be randomized to remote patient managem...

Enrolling
Cardiac Arrhythmia
Device: Remote Patient Management
Device: Standard of Care
Locations recently updated

The purpose of this study is to find out if the investigational drug called omecamtiv mecarbil can reduce the risk of the effects of heart failure, l...

Enrolling
Heart Failure With Reduced Ejection Fraction
Heart Failure
Drug: Placebo
Drug: Omecamtiv Mecarbil (OM)

This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Heal...

Active, not recruiting
COVID-19
Drug: Imatinib
Drug: Artesunate

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