St. Boniface Hospital | Cardiology Research

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409 Tache Avenue, Winnipeg, Manitoba, Canada
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8 of 73
Status: Active
Trial type: Interventional
Funder type: Industry

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation (HERMES)

This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will either get z...

Heart Failure
Drug: Placebo
Drug: Ziltivekimab

This is a multi-center, open-label, prospective single-arm study of reversal of the antiplatelet effects of ticagrelor with bentracimab (PB2452) in p...

Invasive Procedure
Drug: Bentracimab (PB2452) Infusion

Insertion of a central venous access device (CVAD) allows clinicians to easily access the circulation of a patient to administer life-saving interven...

Central Venous Catheter Related Bloodstream Infection
Central Venous Catheter Thrombosis
Device: 4% EDTA
Device: Saline

This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack, have ab...

Myocardial Infarction
Sudden Death
Other: Usual care
Device: Implantable Cardioverter Defibrillator + Usual Care

The purpose of this study is to assess if using the Impella® CP (or Impella® 2.5) device during high-risk PCI in patients with reduced left-sided hea...

Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump

This study is a randomized, double-blind, multicenter, placebo-controlled trial to evaluate the safety and efficacy of a novel therapeutic agent, Nov...

Biological: Placebo
Biological: Novaferon

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiov...

Active, not recruiting
Heart Failure
Other: Placebo
Drug: Finerenone (BAY94-8862)

This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Heal...

Active, not recruiting
Drug: LSALT Peptide
Drug: Imatinib

Trial conditions

Heart Failure (9 trials)
Infarction (5 trials)
Myocardial Infarction (5 trials)
Cardiovascular Diseases (4 trials)
Hemorrhage (4 trials)
Thrombosis (4 trials)
Critical Illness (3 trials)
Aortic Valve Stenosis (2 trials)
Brain Ischemia (2 trials)
COVID-19 (2 trials)

And 90 more

Clinical trials

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