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Sunshine Coast University Private Hospital | Clinical Trials

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Sacituzumab
Etrasimod
LM-108
ARC101
ARV-471
HLX301
BL0020
Nivolumab
IBI343
Trastuzumab

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Active trials

14 of 17 total trials

A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

This is a Phase 1a/b, multicenter, open-label, first-in-human, dose escalation, expansion and extension study to evaluate the safety, tolerability, a...

Enrolling
Locally Advanced Unresectable or Metastatic Solid Tumors
Drug: IBI343
Locations recently updated

The efficacy and safety of zanidatamab in combination with physician's choice of chemotherapy compared with trastuzumab in combination with physician...

Enrolling
Metastatic HER2-positive Breast Cancer
Drug: Trastuzumab
Drug: Gemcitabine

For phase I ,this study is to assess the safety and tolerability, obtain the recommended phase 2 dose (RP2D) and/or Maximum Tolerated Dose (MTD) for...

Not yet enrolling
Advanced Solid Tumours
Drug: LM-168
Drug: Toripalimab

The purpose of this study is to demonstrate that the study drug exposure level of the nivolumab + relatlimab FDC subcutaneous (SC) formulation is not...

Active, not recruiting
Melanoma
Drug: Nivolumab + Relatlimab
Drug: rHuPH20

A study to learn about a new medicine called ARV-471 (PF-07850327) in people who have advanced metastatic breast cancer.

Active, not recruiting
Advanced Breast Cancer
Drug: ARV-471
Drug: Fulvestrant

The purpose of this open-label extension (OLE) study is to evaluate the safety and efficacy of etrasimod in participants with moderately to severely...

Active, not recruiting
Ulcerative Colitis
Drug: Etrasimod

This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of ARC101 in patients with advanced cancer.

Enrolling
Advanced Solid Tumor
Drug: ARC101

The purpose of this study is to assess the safety and tolerability of BGB-21447 (a B-cell leukemia/lymphoma 2 inhibitor, Bcl-2i) in combination with...

Enrolling
Hormone-receptor-positive Breast Cancer
Metastatic Breast Cancer
Drug: Fulvestrant
Drug: BGB-21447

This Phase 1/2, multicenter, first-in-human, open-label, dose-escalation, dose expansion, and clinical expansion study will evaluate the safety, tole...

Enrolling
Locally Advanced or Metastatic Solid Tumors
Non-small Cell Lung Cancer
Drug: HLX301

This is the first in human study of BL0020, and the primary objective is to evaluate the safety and tolerability, and determine the maximum tolerated...

Enrolling
Advanced Solid Tumor
Drug: BL0020

This is a first-in-human, Phase I/II, open-label, multi-centre, dose escalation and expansion study to evaluate the safety, tolerability, pharmacokin...

Enrolling
Advanced Solid Tumor
Drug: An Anti-PD-1 Antibody
Drug: LM-108

The goal of this clinical study is to compare the study drug, sacituzumab govitecan-hziy (SG), versus docetaxel in participants with advanced or meta...

Active, not recruiting
Non-Small Cell Lung Cancer
Biological: Sacituzumab Govitecan-hziy (SG)
Drug: Docetaxel

The goal of this clinical study is to learn more about the study drug, sacituzumab govitecan-hziy (SG), and its dosing in combination with pembrolizu...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: Sacituzumab Govitecan-hziy (SG)
Drug: Pembrolizumab

This is an open label, two-part, multicenter, multi-regional phase I trial to investigate the safety, tolerability, and PK of KGX101 monotherapy and...

Active, not recruiting
Advanced or Metastatic Solid Tumors
Drug: KGX101 and Envafolimab
Drug: KGX101- Cohort 2

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