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Darolutamide
ERAS-254
Androgen
Radium-223 Dichloride
Aplitibart
Naporafenib
KIN-2787
Trametinib
Pembrolizumab
FMC-376

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Data sourced from clinicaltrials.gov

Active trials

6 of 11 total trials
Status recently updated

A First-in-Human Study of HH160 in Participants With Advanced or Metastatic Solid Tumors

This study is evaluating the safety, side effects, how the body processes HH160, and its early anticancer activity when given alone or with other can...

Not yet enrolling
Enrolling
Solid Tumor
Gastroesophageal Adenocarcinoma
Drug: HH160

The goal of this clinical trial is to evaluate FMC-376 in participants with advanced solid tumors with KRAS G12C mutations. This clinical trial will...

Enrolling
Solid Tumor, Adult
Unresectable Solid Tumor
Drug: FMC-376

Stage 1: To select the optimal dose of naporafenib + trametinib to be studied in Stage 2.Stage 2: To compare progression free survival (PFS) and over...

Active, not recruiting
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Researchers are looking for a better way to treat men at high-risk of biochemical recurrence (BCR) of prostate cancer.BCR means that in men who had p...

Active, not recruiting
Biochemically Recurrent Prostate Cancer
Other: Placebo matching darolutamide
Drug: Darolutamide (BAY1841788, Nubeqa)

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-2787 in adults with BRAF/NR...

Active, not recruiting
Melanoma
Solid Tumor, Adult
Drug: KIN-2787 and binimetinib
Drug: KIN-2787

Researchers in this study want to compare how well drug radium-223 dichloride (Xofigo) and androgen receptor pathway inhibitor (ARPI) therapy work in...

Active, not recruiting
Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Drug: ARPI therapy
Drug: Radium-223 dichloride (Xofigo, BAY88-8223)

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