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The Royal Marsden Hospital | Sutton - GI Lymphoma Research Unit

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Active trials

9 of 49 total trials

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer (STAMPEDE2)

STAMPEDE2 is a clinical trial comparing three new treatments with standard of care in people with prostate cancer that has spread to other parts of t...

Enrolling
Prostate Cancer Metastatic
Drug: Androgen Deprivation Therapy (ADT)
Drug: Prednisolone

This is a Phase 1a/1b, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, immune response, and pha...

Active, not recruiting
Bladder Cancer
Melanoma
Drug: Autogene cevumeran
Drug: Atezolizumab

This clinical trial is studying solid tumor cancers. A solid tumor is one that starts in part of your body like your lungs or liver instead of your b...

Enrolling
HER2 Positive Breast Neoplasms
HER2 Low Breast Neoplasms
Drug: disitamab vedotin
Drug: tucatinib

This study will evaluate the safety, pharmacokinetic (PK), pharmacodynamic (PD) activity, and preliminary anti-tumor activity of GDC-9545 as a single...

Active, not recruiting
Breast Cancer
Drug: Palbociclib
Drug: LHRH Agonist

This study is being done to find out if tucatinib with other cancer drugs works better than standard of care to treat participants with HER2 positive...

Enrolling
Colorectal Neoplasms
Drug: levoleucovorin
Drug: leucovorin

This study is researching an investigational drug, odronextamab, in adult patients B-cell non-Hodgkin's lymphoma (B-NHL).The main purpose of this stu...

Enrolling
B-cell Non-Hodgkin Lymphoma (B-NHL)
Drug: Odronextamab

This is a multicenter, randomized, open-label, Phase 3 study in participants with newly diagnosed multiple myeloma to evaluate the benefits of teclis...

Enrolling
Multiple Myeloma
Drug: Lenalidomide
Drug: Teclistamab

This is a global, multicenter, randomized, open-label study, with an adaptive design. The main objective of the study is to measure the efficacy and...

Enrolling
Metastatic Urothelial Cancer
Drug: Pembrolizumab
Drug: BT8009

PERSEUS1 is an open-label, single arm, phase II trial evaluating the efficacy of Pembrolizumab in metastatic castration resistant prostate cancer (mC...

Enrolling
Castration-resistant Prostate Cancer
Drug: Pembrolizumab

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