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The Royal Marsden Hospital | Sutton - GI Lymphoma Research Unit

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Active trials

4 of 41 total trials

A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

This is a Phase 1a/1b, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, immune response, and pha...

Active, not recruiting
Bladder Cancer
Melanoma
Drug: Autogene cevumeran
Drug: Atezolizumab

This study will evaluate the safety, pharmacokinetic (PK), pharmacodynamic (PD) activity, and preliminary anti-tumor activity of GDC-9545 as a single...

Active, not recruiting
Breast Cancer
Drug: Palbociclib
Drug: LHRH Agonist

Primary objective is to assess the anti-tumor activity of single agent odronextamab as measured by the objective response rate (ORR) according to the...

Enrolling
B-cell Non-Hodgkin Lymphoma (NHL)
Drug: Odronextamab

PERSEUS1 is an open-label, single arm, phase II trial evaluating the efficacy of Pembrolizumab in metastatic castration resistant prostate cancer (mC...

Enrolling
Castration-resistant Prostate Cancer
Drug: Pembrolizumab

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