Tiervlei Trial Centre | Cape Town, South Africa

Research site

(Unclaimed)

Location

6th and 7th Floor, The View, Tygervalley Health Centre, Cape Town, Western Cape, South Africa

Site insights

Top conditions

Top treatments

Plozasiran

Upadacitinib

ABT-494

Bococizumab

Elafibranor

Methotrexate

Semaglutide

MTX

Beta

Pemafibrate

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Data sourced from clinicaltrials.gov

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Active trials

11 of 34 total trials

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity (HF-POLARIS)

This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or He...

Enrolling

Obesity

Heart Failure

Drug: NNC0487-0111

Drug: Placebo

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Adults With Rheumatoid Arthritis Who Are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate (SELECT-COMPARE)

The purpose of this study was to assess efficacy, including inhibition of radiographic progression, and safety with upadacitinib versus placebo and v...

Active, not recruiting

Rheumatoid Arthritis

Drug: Placebo for Upadacitinib

Drug: Upadacitinib

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting (ACHIEVE-RAM)

The purpose of this study is to test the efficacy and safety of orforglipron in participants with T2D (type 2 diabetes) who participate in fasting du...

Enrolling

Behavior

Glucagon-Like Peptide-1 Receptor

Drug: Orforglipron

A Study to Evaluate the Safety and Efficacy of MK-1406/CD388 for Prevention of Influenza (MK-1406-005/CD388.SQ.3.06) (ANCHOR)

Approximately one billion cases of seasonal influenza occur annually. Of these, 3 to 5 million illnesses are severe and responsible for up to 650,000...

Active, not recruiting

Influenza

Combination Product: MK-1406

Combination Product: Placebo

Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease (PREVAIL)

This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with Atherosclerotic Cardiovascular Disease (ASCVD)...

Active, not recruiting

Atherosclerotic Cardiovascular Disease

Drug: Obicetrapib

Drug: Placebo

Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension

This is an extension study to evaluate the longer-term safety and efficacy of enlicitide decanoate in adults with hypercholesterolemia who completed...

Active, not recruiting

Hypercholesterolemia

Drug: Enlicitide Decanoate

Phase 3 Inhaled Novaferon Study in Hospitalized Patients With Moderate to Severe COVID-19 (NOVATION-1)

This study is a randomized, double-blind, multicenter, placebo-controlled trial to evaluate the safety and efficacy of a novel therapeutic agent, Nov...

Enrolling

Covid19

Biological: Placebo

Biological: Novaferon

Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia (MUIR-3)

This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with hypertriglyceridemia (HTG). A...

Active, not recruiting

Hypertriglyceridemia

Drug: Placebo

Drug: Plozasiran Injection

Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH) (ESSENCE)

Semaglutide is a medicine studied in patients with NASH. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabe...

Active, not recruiting

Non-alcoholic Steatohepatitis

Drug: Placebo

Drug: Semaglutide

Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) (ELATIVE)

The participants of this study will have confirmed Primary Biliary Cholangitis (PBC) with inadequate response or intolerance to ursodeoxycholic acid...

Active, not recruiting

Primary Biliary Cirrhosis

Drug: Placebo

Drug: Elafibranor 80mg

Study of Plozasiran in Adults With Severe Hypertriglyceridemia (SHASTA-4)

This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with severe hypertriglyceridemia (...

Active, not recruiting

Severe Hypertriglyceridemia

Drug: Placebo

Drug: Plozasiran Injection