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Trustees of The University of Pennsylvania | Penn Blood Disorder Center

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Active trials

2 of 2 total trials

A Study to Evaluate Prospective Efficacy and Safety Data of Current FIX Prophylaxis Replacement Therapy in Adult Hemophilia B Subjects (FIX:C≤2%) or Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Subjects (FVIII:C≤1%)

To establish baseline prospective efficacy data of current FIX prophylaxis replacement therapy in the usual care setting of hemophilia B subjects, wh...

Active, not recruiting
Hemophilia B
Hemophilia A
Drug: Standard of Care FIX Replacement therapy
Drug: Standard of Care FVIII Replacement therapy

This study will evaluate the efficacy and safety of PF-06838435 (a gene therapy drug) in adult male participants with moderately severe to severe hem...

Active, not recruiting
Hemophilia B
Biological: PF-06838435/ fidanacogene elaparvovec

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