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Universitätsklinikum Freiburg | Klinik fur Dermatologie und Venerologie

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Darolutamide
Etavopivat
5-Fluorouracil
Eteplirsen
BC 007
Octreotide
Leucovorin
Sacituzumab
Trabectedin
Atezolizumab

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Active trials

19 of 35 total trials

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

This is an open-label, two-part Phase 2 study investigating CGT9486 for the treatment of patients with Advanced Systemic Mastocytosis (AdvSM), includ...

Enrolling
SM With an Associated Hematologic Neoplasm (SM-AHN)
Aggressive Systemic Mastocytosis (ASM)
Drug: bezuclastinib

The purpose of this study is to determine if an investigational drug can prevent Bronchopulmonary Dysplasia, reducing the burden of chronic lung dise...

Enrolling
Chronic Lung Disease of Prematurity
Intraventricular Hemorrhage
Drug: OHB-607

This is a randomized, double-blind, placebo-controlled, repeat-dose, multicenter trial. Participants will be screened within 6 weeks prior to the Bas...

Enrolling
Diffuse Cutaneous Systemic Sclerosis
Sclerosis, Systemic
Drug: Placebo
Drug: HZN-825 QD
Locations recently updated

The primary efficacy objective:To evaluate the effect of daxdilimab compared with placebo in reducing disease activity at Week 24.The secondary effic...

Enrolling
Idiopathic Inflammatory Myositis
Drug: Daxdilimab
Drug: Placebo

This study will look at how well CagriSema helps people with type 2 diabetes lower their blood sugar and body weight. CagriSema is a new investigatio...

Enrolling
Type 2 Diabetes
Drug: Semaglutide
Drug: Cagrilintide

This clinical trial is a Phase 2/3 study that will evaluate the efficacy and safety of etavopivat and test how well etavopivat works compared to plac...

Enrolling
Sickle Cell Disease
Drug: Placebo Tablets
Drug: Etavopivat Tablets High dose

This study will be comprised of 2 parts: Part 1 (dose escalation) will be conducted to evaluate the safety and tolerability of 2 doses (100 milligram...

Active, not recruiting
Muscular Dystrophy, Duchenne
Drug: Eteplirsen

This study will evaluate the efficacy, safety, and pharmacokinetics of obinutuzumab compared with placebo in patients with International Society of N...

Active, not recruiting
Lupus Nephritis
Drug: Placebo
Drug: MMF

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of RO7303509 treatment in participants with systemic scl...

Enrolling
Systemic Sclerosis
Drug: RO7303509
Drug: Placebo

Researchers are looking for a better way to treat people who have macular edema secondary to retinal vein occlusion (RVO).In people with RVO, a blood...

Enrolling
Macular Edema Secondary to Retinal Vein Occlusion
Drug: Aflibercept, VEGF Trap-Eye(Eylea, BAY86-5321)_2 mg
Drug: Sham
Locations recently updated

This study is open to adults who are at least 18 years old and have a body mass index (BMI)bof 27 kg/m2 or more. People can take part if they have ca...

Enrolling
Obesity
Drug: Placebo
Drug: survodutide

The MINERVA Trial aims to evaluate safety, efficacy and quality of life (QoL) for the combination of Abemaciclib with an Aromatase Inhibitor or Fulve...

Enrolling
HER2-negative Metastatic Breast Cancer
Hormone Receptor-positive Metastatic Breast Cancer
Drug: Abemaciclib + Aromatase Inhibitor
Drug: Abemaciclib + Fulvestrant

This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monothe...

Enrolling
Low-grade Glioma
Drug: Tovorafenib
Drug: Chemotherapeutic Agent
Locations recently updated

This study is open to adults aged 18 and over who have just had a heart attack. The purpose of this study is to find out whether a medicine called BI...

Enrolling
Myocardial Infarction
Drug: BI 765845
Drug: Placebo matching BI 765845

The trial aims to demonstrate the non-inferiority of subcutaneous to intravenous isatuximab administration in transplant-eligible patients with newly...

Enrolling
Multiple Myeloma
Drug: Lenalidomide
Drug: Dexamethasone

Phase III, prospective, multi-center, randomized, open label, parallel group, study in patients with HER2-negative breast cancer with residual diseas...

Active, not recruiting
Triple Negative Breast Cancer
HER2-negative Breast Cancer
Drug: Sacituzumab govitecan
Drug: Cisplatin

The aim of this study is to provide darolutamide treatment to patients who participated in a previous study with darolutamide supported by Bayer and...

Enrolling
Cancer
Drug: Darolutamide (Nubeqa, BAY1841788)

Urolithiasis is an extremely common disease affecting about 12% of the world population with increasing tendency. Urinary stones are sediments that f...

Enrolling
Lithotripsy, Laser
Other: Laser lithortripsy
Device: Laser lithotripsy with stone recognition

This study is an interventional, randomized, multinational, multicenter, double-blind, phase 2 study with a follow-up period of 90 days.The intension...

Active, not recruiting
Long Covid
Drug: BC 007 or matching placebo

Trial sponsors

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