University Medical Center of Southern Nevada | UMC Hospital, Clinical Trials Office

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1800 W. Charleston Boulevard, Las Vegas, Nevada, United States of America
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10 of 359
Status: Active
Trial type: Interventional
Funder type: Industry

A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery

This phase II trial studies the side effects and how well nirogacestat works in treating patients less than 18 years of age with desmoid tumors that...

Active, not recruiting
Desmoid Fibromatosis
Unresectable Desmoid Fibromatosis
Procedure: Magnetic Resonance Imaging
Other: Quality-of-Life Assessment

The purpose of this clinical trial (NCT02627196) is to develop valid scientific evidence for safety and effectiveness of Baroreflex Activation Therap...

Active, not recruiting
Heart Failure
Device: BAROSTIM NEO® System
Drug: Medical Management

Subjects meeting the inclusion/exclusion criteria will wear the µCor for at least 90 days. During the study, clinic follow up will occur every 30 day...

Active, not recruiting
Heart Failure
Device: µCor

RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by lowering the amount of es...

Active, not recruiting
Breast Cancer
Drug: Letrozole
Other: Placebo

A Phase 2a, randomized, double-blind, placebo-controlled, multiple ascending dose study in patients who are hospitalized with presumed pneumonia requ...

COVID-19 Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
Drug: AV-001 Placebo Injection
Drug: AV-001 Injection

The investigators hypothesize that the combination of eflornithine and sulindac will be effective in reducing a three-year event rate of adenomas and...

Active, not recruiting
Colorectal Neoplasms
Drug: eflornithine & sulindac placebo
Drug: Eflornithine placebo & sulindac placebo

A randomized, double-blind, placebo-controlled Phase 2/3 Study of LAU-7b against confirmed COVID-19 Disease in hospitalized patients at a higher risk...

Active, not recruiting
COVID-19 Disease
Drug: Placebo oral capsule
Drug: LAU-7b

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in pa...

Prognostic Stage IA Breast Cancer AJCC v8
Prognostic Stage IB Breast Cancer AJCC v8
Other: Questionnaire Administration
Other: Quality-of-Life Assessment

This study is a prospective, single-arm, multi-center, open-label, staged clinical study.Overall Objective:To evaluate the safety and effectiveness o...

Active, not recruiting
Rectal Lesion
Rectal Polyp
Device: ColubrisMX Endoluminal Surgical (ELS) System

This phase II trial studies how well vismodegib, focal adhesion kinase (FAK) inhibitor GSK2256098, and capivasertib work in treating patients with me...

Recurrent Meningioma
NF2 Gene Mutation
Drug: Abemaciclib
Drug: Vismodegib

Trial conditions

Carcinoma (70 trials)
Cancer (49 trials)
Breast Cancer (48 trials)
Leukemia (40 trials)
Lung Cancer (35 trials)
Recurrence (35 trials)
Lymphoma (33 trials)
Adenocarcinoma (24 trials)
Non-Small-Cell Lung Carc... (24 trials)
Precursor Cell Lymphobla... (24 trials)

And 90 more

Clinical trials

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