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University of Iowa Hospitals | Infectious Diseases Department

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Top treatments

Armodafinil
Pembrolizumab
AS1413
ASP1002
ASP2074
Daclizumab
Rucaparib
Gemcitabine
Cytarabine
APL-2

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Active trials

6 of 25 total trials

A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy (ATHENA)

This is a Phase 3, randomized, multinational, double-blind, dual placebo-controlled, 4-arm study evaluating rucaparib and nivolumab as maintenance tr...

Active, not recruiting
FIGO Stage III-IV
Newly Diagnosed
Drug: Placebo Oral Tablet
Drug: Rucaparib

The main aims of this study are:* To check the safety of ASP1002 in people with certain solid tumors.* To check if the people can tolerate ASP1002.*...

Enrolling
Advanced Solid Tumors
Drug: ASP1002

ASP1012 is a type of virus called an oncolytic virus which is used to treat some cancers.ASP1012 was changed in a laboratory to infect and kill cance...

Enrolling
Solid Tumor
Drug: ASP1012
Drug: Pembrolizumab

This study will enroll individuals who have:* Completed primary series of mRNA COVID-19 vaccine, and* An antibody response ≤ 2500 U/mL measured at le...

Active, not recruiting
Liver Transplant Recipients
Kidney Transplant Recipients
Drug: SOC IS Reduction
Biological: Moderna COVID-19 Vaccine 2023-2024

The goal of this trial is to learn about the antibody acasunlimab (an antibody also known as GEN1046) when it is used alone and when it is used toget...

Active, not recruiting
Endometrial Carcinoma
Squamous Cell Carcinoma of the Head and Neck
Biological: Acasunlimab in combination with pembrolizumab and standard chemotherapy (in separate expansion cohorts)
Biological: Acasunlimab

The primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected...

Enrolling
Advanced Unresectable Solid Tumor
Metastatic Solid Tumor
Drug: Toripalimab
Drug: TAB004

Trial sponsors

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