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University of Michigan | Kellogg Eye Center

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NT-501
Linsitinib
Zimura
AU-011
Lidocaine
Elamipretide

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Active trials

4 of 23 total trials

A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) (LIDS)

The overall objective is to study the safety, pharmacokinetics and efficacy of linsitinib (a small molecule IGF-1R inhibitor) administered orally twi...

Active, not recruiting
Thyroid Diseases
Graves Ophthalmopathy
Drug: Placebo
Drug: Linsitinib

The study consists of a randomized double-masked, placebo-controlled, parallel-group, multicenter trial with an optional open-label treatment period...

Active, not recruiting
Thyroid Eye Disease
Other: Placebo
Biological: Teprotumumab

The goal of this clinical trial is to evaluate the efficacy, safety and pharmacokinetics of elamipretide in subjects with dry age-related macular deg...

Enrolling
Age Related Macular Degeneration (ARMD)
Drug: Elamipretide
Drug: Placebo

The primary objective is to assess the safety and tolerability of bel-sar treatment in subjects with metastases to the choroid from any primary carci...

Enrolling
Eye Cancer
Primary Cancer
Device: SCS Microinjector
Device: Laser

Trial sponsors

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Spark Therapeutics logo

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