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University of Michigan | Kellogg Eye Center

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NT-501
Zimura
Lidocaine
Linsitinib

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Active trials

3 of 20 total trials

A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) (LIDS)

The overall objective is to study the safety, pharmacokinetics and efficacy of linsitinib (a small molecule IGF-1R inhibitor) administered orally twi...

Active, not recruiting
Thyroid Diseases
Graves Ophthalmopathy
Drug: Placebo
Drug: Linsitinib

The study consists of a randomized double-masked, placebo-controlled, parallel-group, multicenter trial with an optional open-label treatment period...

Enrolling
Thyroid Eye Disease
Other: Placebo
Biological: Teprotumumab

The purpose of this study is to evaluate the safety and efficacy of avacincaptad pegol intravitreal injection compared to Sham in participants with a...

Active, not recruiting
Stargardt's Macular Dystrophy
Drug: Sham
Drug: avacincaptad pegol

Trial sponsors

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Spark Therapeutics logo

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