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University of Rochester Medical Center | Wilmot Cancer Institute

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(Unclaimed)

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Top conditions

Top treatments

Melphalan
LY3484356
Busulfan
Cyclophosphamide
Fludarabine
Ribociclib
Lisinopril
Estrogen
Cisplatin
Imlunestrant

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Active trials

6 of 15 total trials

A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

The purpose of this study is to assess the safety and efficacy of Navlimetostat (BMS-986504), a selective, MTA-cooperative PRMT5 inhibitor, in combin...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
Drug: Placebo
Drug: Nab-paclitaxel

This study will include two groups of patients: Cohort 1 and Cohort 2.Cohort 1: will help researchers learn how a medicine called imlunestrant (LY348...

Enrolling
Breast Neoplasms
Drug: Goserelin
Drug: Imlunestrant

The main purpose of this study is to learn more about the safety, side effects, and effectiveness of LOXO-783. LOXO-783 may be used to treat breast c...

Active, not recruiting
Breast Cancer
Drug: Anastrozole, Exemestane, or Letrozole
Drug: Paclitaxel

The reason for this study is to see if the study drug LY3484356 alone or in combination with other anticancer therapies is safe and effective in part...

Active, not recruiting
Endometrial Cancer
Breast Cancer
Drug: Trastuzumab
Drug: Everolimus

The purpose of this study is to test a new medicine, vepugratinib, in comparison with placebo, to see if it is safe and can help people with a bladde...

Enrolling
Urinary Bladder Neoplasms
Neoplasm Metastasis
Drug: Vepugratinib
Drug: EV

Older patients with diffuse large B- cell lymphoma (DLBCL) do not have the same rates of disease control as younger patients and are at risk for toxi...

Enrolling
Diffuse Large B-Cell Lymphoma (DLBCL)
Drug: Mosunetuzumab
Device: ClonoSEQ

Trial sponsors

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