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University of Virginia | UVA Center for Diabetes Technology

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Hydroxyurea
Bomedemstat
Tipiracil
Trifluridine
Centanafadine
Bevacizumab
Lomustine
IMG-7289
IMGN151
Zanubrutinib

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Active trials

7 of 8 total trials

A Randomized Trial Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Over-Expressed Refractory Metastatic Colorectal Cancer

Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide and in China. The purpose of this study is to assess adverse even...

Enrolling
Metastatic Colorectal Cancer
Drug: ABBV-400
Drug: Trifluridine/Tipiracil

This is a study evaluating the safety and efficacy of bomedemstat (MK-3543) compared with the best available therapy (BAT) in participants with essen...

Enrolling
Essential Thrombocythemia
Drug: Interferon alfa/pegylated interferon alfa
Drug: Busulfan
Locations recently updated

The goal of this study is to compare how well sonrotoclax plus zanubrutinib works versus zanubrutinib plus placebo in treating adults with relapsed/r...

Enrolling
B Cell Lymphoma
Mantle Cell Lymphoma
Drug: Sonrotoclax
Drug: Placebo

The trial aims to collect safety, efficacy, exposure, dose- response, pharmacokinetic and pharmacodynamic information of the combination of L19TNF an...

Enrolling
Glioblastoma
Drug: L19TNF
Drug: Lomustine
Locations recently updated

The purpose of this study is to evaluate the efficacy and safety of bomedemstat compared with hydroxyurea in cytoreductive therapy naïve essential th...

Enrolling
Essential Thrombocythemia
Drug: Bomedemstat
Drug: Hydroxyurea

The purpose of this study is to evaluate the safety and effectiveness of ARTIA in adult participants undergoing immediate, two-stage, implant-based b...

Enrolling
Breast Reconstruction
Other: No Intervention
Device: ARTIA Reconstructive Tissue Matrix

IIMGN151-1001 is a Phase 1, first in human, open-label dose-escalation, optimization, and expansion study designed to characterize the safety, tolera...

Enrolling
Endometrial Cancer
Primary Peritoneal Carcinoma
Drug: IMGN151

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