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Valiance Clinical Research | Tarzana, CA

Research site
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At Valiance Clinical Research, we’re redefining what clinical trials can be—where scientific excellence meets compassion, and every study begins with integrity. Founded by physicians and researchers determined to put patients first, we combine deep medical expertise with a personal, transparent approach that accelerates innovation without losing the human touch.

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Top conditions

Top treatments

Dapagliflozin
LY3298176
AZD7760
Vicadrostat
Zilebesiran
Clazakizumab
Formoterol Fumarate
Empagliflozin
Finerenone
Zibotentan

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Active trials

17 of 17 total trials

A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure. (BaxDuo-Baltic)

International, Multicenter and Double-Blind study. The purpose is to measure the effect of baxdrostat in combination with dapagliflozin compared with...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Baxdrostat/Placebo

International, Multicenter, Double-Blind, Placebo-Controlled and Event-driven study to assess efficacy, safety and Tolerability of Baxdrostat in comb...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Placebo/dapagliflozin

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN.This s...

Active, not recruiting
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Dapagliflozin in combination with placebo

PARAMOUNT is a prospective randomized open-label trial testing the hypothesis that a personalized management strategy in symptomatic patients with su...

Enrolling
Coronary Artery Disease
Device: Cleerly Labs and Cleerly ISCHEMIA

TRANSFORM is a prospective, randomized, open blinded endpoint (PROBE), event-driven, pragmatic trial in patients who are at increased risk for athero...

Enrolling
Diabetes Mellitus, Type 2
Metabolic Syndrome
Device: The Cleerly CAD Staging System

This study will evaluate the effect of triple ICS/LAMA/LABA therapy with BGF MDI 320/14.4/9.6 μg on cardiopulmonary outcomes relative to LAMA/LABA th...

Enrolling
COPD (Chronic Obstructive Pulmonary Disease)
Drug: BGF MDI 320/14.4/9.6 μg
Drug: GFF MDI 14.4/9.6 μg

This study will investigate the effect of tirzepatide on the reduction of morbidity and mortality in adults living with obesity and provide additiona...

Active, not recruiting
Overweight
Obesity
Drug: Placebo
Drug: Tirzepatide

The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of AZD7760 when given as an intravenous infusion to healthy participant...

Enrolling
Staphylococcus Aureus
Drug: AZD7760
Other: Placebo

Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients with heart failure and reduced ejection fraction (HF...

Enrolling
Heart Failure
Drug: Finerenone
Drug: Placebo

This study is researching experimental drugs called trevogrumab and garetosmab (called "study drugs") in combination with another drug, semaglutide (...

Active, not recruiting
Obesity
Drug: Matching Placebo-Trevogrumab
Drug: Matching Placebo-Garetosmab

This study is open to adults with chronic kidney disease (CKD) that is at risk of getting worse. People who have taken a specific type of medication...

Enrolling
Chronic Kidney Disease
Drug: Vicadrostat
Drug: Empagliflozin

This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study. Part 1 (phase 2b) is a do...

Enrolling
Atherosclerotic Cardiovascular Disease
Atherosclerotic Cardiovascular Disease in Patients With ESKD
Drug: Placebo
Drug: CSL300

The purpose of this trial is to investigate the efficacy and safety of dapansutrile (OLT1177®) tablets in subjects with an acute gout flare.

Enrolling
Gouty Arthritis
Gout Attack
Other: Placebo Tablet
Drug: Dapansutrile

This study is researching experimental drugs called ALN-ANG3 and evinacumab (called "study drugs"). The study is focused on participants who have dia...

Enrolling
Diabetic Kidney Disease (DKD)
Drug: Evinacumab
Drug: ALN-ANG3 placebo

This is a Phase III, randomised, multicentre, double-blinded study to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagli...

Active, not recruiting
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin
Status recently updated

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent...

Enrolling
Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Chronic Kidney Disease (CKD)
Drug: Retatrutide
Drug: Placebo

The purpose of this study is to evaluate whether zilebesiran versus placebo reduces the risk of cardiovascular (CV) death, nonfatal myocardial infarc...

Enrolling
High Risk Cardiovascular Disease
Hypertension
Drug: Zilebesiran
Drug: Placebo

Trial sponsors

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