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Valkyrie Clinical Trials | Los Angeles, CA

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Pembrolizumab
Tislelizumab
Lenalidomide
Zongertinib
Ezabenlimab
Capecitabine
Oxaliplatin
Zanubrutinib
Gemcitabine
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Active trials

72 of 91 total trials
Locations recently updated

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies (CaDAnCe-101)

Study consists of two main parts to explore BGB-16673 recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalation...

Enrolling
Waldenström Macroglobulinemia
Marginal Zone Lymphoma
Drug: BGB-16673

Multi-site, open-label, first-in-human study with 2 parts (dose escalation and dose expansion) in subjects with selected advanced solid tumours

Enrolling
Solid Tumours
Drug: ODM-212
Locations recently updated

The purpose of this study is to assess the safety, tolerability, and efficacy of sonrotoclax as monotherapy and in various combinations in patients w...

Enrolling
Relapsed/Refractory Multiple Myeloma
Drug: Pomalidomide
Drug: Carfilzomib

The main objective of the study is to characterize safety and efficacy of 2 dose levels of anvumetostat by investigator, and to evaluate anvumetostat...

Active, not recruiting
MTAP-deleted NSCLC
Drug: anvumetostat

This is an adaptive Phase 2, open-label, randomized, multi-center study evaluating up to 2 regimens of PCS6422 with capecitabine (Cap) vs. standard d...

Enrolling
Breast Cancer
TNBC - Triple-Negative Breast Cancer
Drug: Capecitabine
Drug: PCS6422 and capecitabine

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pan...

Enrolling
G12D Mutated KRAS
Pancreatic Ductal Adenocarcinoma (PDAC)
Drug: VS-7375
Drug: cetuximab

The purpose of this study is to learn about the effects of a study medicine, WGI-0301 to find the best dose for treating solid tumors, and to see how...

Enrolling
Advanced Solid Tumors
Drug: WGI-0301

The purpose of this study is to evaluate how well JNJ-79635322 works when compared with teclistamab.

Enrolling
Multiple Myeloma
Drug: Teclistamab
Drug: JNJ-79635322

This is a Phase 1b/2 study to investigate the efficacy and safety of alcestobart (LBL-007) plus tislelizumab when administered in combination with be...

Active, not recruiting
Unresectable or Metastatic Microsatellite Stable/Mismatch Repair Proficient Colorectal Cancer
Drug: Alcestobart
Drug: Bevacizumab or Bevacizumab biosimilar

This trial is a Phase II study. The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of AK112 with or without AK117 in...

Active, not recruiting
Metastatic Colorectal Cancer
Drug: Leucovorin
Drug: 5-fluorouracil

The purpose of this study is to compare anti-tumor activity of amivantamab in addition to pembrolizumab and carboplatin versus pembrolizumab, 5-fluor...

Enrolling
Squamous Cell Carcinoma of Head and Neck
Drug: Carboplatin
Drug: Cisplatin

The primary purpose of the study is to assess how well amivantamab in combination with lazertinib or in combination with chemotherapy works (antitumo...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Chemotherapy: Carboplatin
Drug: Lazertinib
Locations recently updated

This study is being done to see if a drug called disitamab vedotin, alone or with pembrolizumab, works to treat HER2 expressing urothelial cancer. It...

Enrolling
Urothelial Carcinoma
Drug: pembrolizumab
Drug: disitamab vedotin

The purpose of this clinical study is to learn about the safety and effects of the study medicine (called disitamab vedotin) for the possible treatme...

Enrolling
Breast Cancer
Breast Neoplasms
Drug: Disitamab vedotin
Locations recently updated

This clinical trial is studying advanced or metastatic solid tumors. Once a solid tumor has grown very large in one spot or has spread to other place...

Active, not recruiting
Ovarian Neoplasms
Carcinoma, Non-Small-Cell Lung
Drug: disitamab vedotin

The purpose of this study is to assess the efficacy and safety of iza-bren, a bi-specific antibody-drug conjugate against EGFR and HER3 with a topois...

Enrolling
Breast Neoplasms
Drug: Paclitaxel
Drug: Iza-bren

This phase 1 study will investigate the safety, dosing, and initial antitumor activity of JZP815 in participants with advanced or metastatic solid tu...

Enrolling
Solid Tumor
Metastatic Cancer
Drug: JZP815

The purpose of this study is to evaluate the efficacy and safety of lurbinectedin in combination with durvalumab for the treatment of participants wi...

Enrolling
Extensive-stage Small-cell Lung Cancer
Drug: Lurbinectedin
Drug: Durvalumab

The purpose of this study is to find out whether treatment with pasritamig and docetaxel prolongs radiographic progression free survival (rPFS) (the...

Enrolling
Prostatic Neoplasms, Castration-Resistant
Drug: Docetaxel
Drug: Prednisone

B-cell Lymphoma is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections). This study will...

Active, not recruiting
Diffuse Large B-Cell Lymphoma
Drug: Rituximab
Drug: Oxaliplatin

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