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Velocity Clinical Research | Raleigh, NC

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Ofatumumab
Remibrutinib
Frexalimab
Ocrelizumab
CVN424
SAR441344
Teriflunomide
ABBV-552

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Active trials

8 of 10 total trials
Locations recently updated

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation (SOSTOS)

This study will evaluate if relapsing-remitting MS patients that have not had a relapse in the past year would benefit from a switch to ofatumumab ve...

Active, not recruiting
Relapsing-Remitting Multiple Sclerosis
Drug: Disease modifying treatment (DMT)
Drug: Ofatumumab

This study will measure how adults with CIDP receiving IVIg treatment adjust to efgartigimod PH20 SC. The study duration for each participant will be...

Active, not recruiting
Chronic Inflammatory Demyelinating Polyneuropathy
Biological: Efgartigimod PH20 SC
Locations recently updated

The purpose of this Phase 3b study is to assess the efficacy, safety and tolerability of remibrutinib after switching from ocrelizumab and compared t...

Enrolling
Relapsing Multiple Sclerosis
Drug: Remibrutinib oral treatment
Drug: Ocrelizumab

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)

Active, not recruiting
Relapsing Multiple Sclerosis
Drug: Teriflunomide
Drug: Remibrutinib

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the dis...

Enrolling
Multiple Sclerosis
Drug: Frexalimab
Drug: Placebo

The purpose of this study is to collect long-term safety, tolerability, effectiveness and health outcomes data in eligible subjects who have particip...

Active, not recruiting
Relapsing Multiple Sclerosis
Biological: 23-valent pneumococcal polysaccharide vaccine (23-PPV)
Biological: Tetanus toxoid (TT) containing vaccine (Td, Tdap)

This study will evaluate the pharmacokinetics, pharmacodynamics, safety and tolerability of a new dosage of ofatumumab compared to the approved dosag...

Active, not recruiting
Relapsing Multiple Sclerosis (RMS)
Biological: Ofatumumab approved dose
Biological: Ofatumumab new dose

This is a randomized, double-blind, placebo-controlled, multicenter study in participants with Parkinson's disease (PD) with motor fluctuations. Part...

Enrolling
Parkinson Disease
Drug: Placebo
Drug: CVN424 75 mg

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