Washington Institute for Coagulation | Seattle, WA

Research site
701 Pike Street Suite 1900, Seattle, Washington, United States of America

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Active trials

6 of 6 total trials

A Study of Recombinant AAV2/6 Human Factor 8 Gene Therapy SB-525 (PF-07055480) in Subjects With Severe Hemophilia A

The purpose of the study is to evaluate the safety, tolerability and time-course profile of FVIII activity after dosing with SB-525 (PF-07055480)

Active, not recruiting
Hemophilia A
Biological: SB-525 (PF-07055480)

This is a multicenter, open-label, single-arm study designed to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of emicizumab i...

Active, not recruiting
Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor
Hemophilia A
Drug: Emicizumab

This is an open-label, single-dose, multi-center, multinational trial to demonstrate the efficacy of AMT-061 and to further describe its safety profi...

Active, not recruiting
Hemophilia B
Biological: Factor IX (FIX)
Genetic: AAV5-hFIXco-Padua

A study to learn about the long-term safety and efficacy of giroctocogene fitelparvovec or fidanacogene elaparvovec in patients with hemophilia A or...

Hemophilia B
Hemophilia A
Diagnostic Test: Testing of hepatic AAV Vector integration

Treatment with PF-06741086 is anticipated to demonstrate a clinically relevant advantage and/or a major contribution to patient care in comparison to...

Active, not recruiting
Hemophilia B
Hemophilia A
Drug: PF-06741086

C3731003 is a pivotal Phase 3 study to evaluate the clinical efficacy and safety of a single IV infusion of PF-07055480 / giroctocogene fitelparvovec...

Active, not recruiting
Hemophilia A
Biological: PF-07055480 (giroctocogene fitelparovec): Recombinant AAV2/6 Human Factor VIII Gene Therapy

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