West Coast Research | Dublin, CA

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7033 Village Parkway, Dublin, California, United States of America

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AMG 451

Data sourced from clinicaltrials.gov

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Active trials

8 of 10 total trials

A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)

The co-primary objectives of the study are to:* Evaluate the efficacy of rocatinlimab compared with placebo at Week 24, assessed using Validated Inve...

Active, not recruiting
Atopic Dermatitis
Other: Placebo
Drug: Rocatinlimab
Locations recently updated

The primary objective of this study is to describe the long-term safety and tolerability of rocatinlimab in participants with moderate-to-severe AD.

Atopic Dermatitis
Drug: Rocatinlimab
Other: Placebo

The main purpose of this study is to evaluate the safety and immunogenicity of mRNA-1345 RSV vaccine when coadministered with a high dose (HD) quadri...

Active, not recruiting
Respiratory Syncytial Virus
Biological: Fluzone HD
Biological: Placebo

The purpose of this study is to understand the safety and effects of a combined influenza and COVID-19 vaccine. This combined vaccine is compared to...

Active, not recruiting
Biological: COVID-19 Vaccine
Biological: Investigational influenza vaccine

The purpose of this clinical protocol is to learn about the safety, tolerability, and immunogenicity of new BNT162b2 RNA-based vaccine candidates tar...

Active, not recruiting
SARS-CoV-2 Infection
Biological: BNT162b2 (Omi XBB.1.5)

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults wi...

Active, not recruiting
Coronary Heart Disease (CHD)
Drug: Evolocumab
Drug: Placebo

The purpose of this study is to evaluate whether the Dermal Cooling System can be used to elicit an improvement in the cosmetic appearance or physica...

Skin Lesion
Device: Dermal Cooling System

Efficacy Study: This randomized, double-blinded, placebo-controlled Phase 3 study is designed to assess the safety, immunogenicity, and efficacy of a...

Lower Respiratory Tract Illness
Biological: Placebo
Biological: RSVpreF

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