0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.

Mahidol University

Status and phase: Unknown; Phase 4

Conditions: Postoperative Pain

Treatments: Drug: Spinal morphine

Study type: Interventional

Funder types: Other

Identifiers

NCT01979354

552/2556(EC3)

Details and patient eligibility

About

Postoperative pain after Video-assisted Thoracoscopic Surgery (VAT) is still debating. Therefore the investigators conduct a study comparing 0.15 mg spinal morphine and control group in term of analgesia.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 year or over
• Patient ASA physical status I-III.
• Scheduled for video-assisted thoracoscopic lobectomy or blebectomy with pleurectomy or pleural abrasion
• Can operate a patient-controlled analgesia (PCA) device.

Exclusion criteria

• Known hypersensitivity to morphine
• History of bleeding tendency.
• Known case of infection at the back
• Patient refuse for spinal anesthesia
• History of cerebrovascular disease.
• Need mechanical ventilatory support during postoperative period

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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40 participants in 2 patient groups

Spinal morphine

Active Comparator group

Description:

0.15 mg spinal morphine

Treatment:

Drug: Spinal morphine

Control

No Intervention group

Description:

No spinal morphine