1 Year MRI Followup in Facioscapulohumeral Muscular Dystrophy (FSHD)

Grete Andersen, MD

Status: Completed

Conditions: FSHD - Facioscapulohumeral Muscular Dystrophy

Treatments: Other: MRI

Study type: Observational

Funder types: Other

Identifiers

NCT02159612

H-3-2012-163 (fsh)

Details and patient eligibility

About

An investigation of disease progression in adult danish patients with facioscapulohumeral muscular dystrophy. The disease progression is followed for a year with two test-days, including functional muscle tests and a MRI scan of muscles in the back and legs.

Full description

A cohort of adult danish patients with facioscapulohumeral muscular dystrophy is invited to perform a MRI scan to describe the relation between backpain and disease affection in back muscles. After one year they are re-invited to perform another MRI scan to follow the disease progression.

The MRI scan is done to measure the quantity and quality of the muscles in the back, thigh and calf. Further, investigators investigate the muscle function by measuring of muscle strength in legs and in the back together with three functional tests. A walking test (6MWT), a stair test (14SST), and a chair test (5-TSTST). Self-assessment of back pain is measured by a standardized questionnaire about backpain.

Enrollment: 45 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with FSHD type 1

Exclusion criteria

• Pregnant or breastfeeding women.
• Patients with claustrophobia.
• Patients with implanted metallic parts in the body.

Trial design

45 participants in 1 patient group

FSHD

Description:

A cohort of adult danish patients with facioscapulohumeral muscular dystrophy is invited to perform a MRI scan.

Treatment:

Other: MRI