12-Week-Combined Physical Training In Heart Failure Patients

U

Universidade Estadual Paulista Júlio de Mesquita Filho

Status

Completed

Conditions

Heart Failure Patients

Treatments

Other: Combined aerobic and resistance physical training program

Study type

Interventional

Funder types

Other

Identifiers

NCT02571270
UEPJMF-001

Details and patient eligibility

About

Purpose: Physical exercise exerts favorable impact on functional capacity (FC) and quality of life (QL) in patients with heart failure (HF). It is believed that the combined aerobic and resistance physical training (CPT) supervised by physical educator is better than only prescription of unsupervised exercise. The aim of this study is to compare the effects of a CPT program on the FC and QL of HF patients with reduced ejection fraction (HFREF) with the practice medical routine prescription of regular physical activity and correlate these findings with clinical and echocardiographic variables. Methods: A longitudinal prospective study included 28 consecutive HFREF patients randomly divided in two age- and gender- matched groups: Trained Group (TG, n = 17), patients undergoing 12 weeks of supervised CPT and Non Trained Group (NTG, n = 11), patients receiving only medical prescription to practice regular physical exercise. All patients were submitted to clinical evaluation, transthoracic echocardiography, Cooper walk test and QL questionnaire before and after the study protocol. Student t test or Mann-Whitney test were performed for groups comparison and correlation tests for the same group variable associations.

Enrollment

28 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients with heart failure with LVEF <50%;
  • Patients with optimized drug therapy;
  • Age over 18 years.

Exclusion criteria

  • Heart failure NYHA class IV and/or Stage D;
  • Decompensated HF in the last three months;
  • Atrial fibrillation and/or implantable device at the moment of inclusion;
  • Patients with chronic obstructive pulmonary disease (COPD);
  • Patients with biomechanical limitations of physical activity.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

28 participants in 4 patient groups

Active lifestyle
Active Comparator group
Description:
Active lifestyle involves nutritional education, physical activity and active recreation.
Treatment:
Other: Combined aerobic and resistance physical training program
Lifestyle counseling
Active Comparator group
Description:
Lifestyle counseling helps patients to have better self-care.
Treatment:
Other: Combined aerobic and resistance physical training program
secondary prevention
Active Comparator group
Description:
Secondary prevention it is essential to prevent a new unfavorable event.
Treatment:
Other: Combined aerobic and resistance physical training program
survival
Active Comparator group
Description:
The survival of patients with heart failure may increase with exercise training.
Treatment:
Other: Combined aerobic and resistance physical training program

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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