14 Weeks Exercise Training on Lean Women With and Without PCOS

University of Copenhagen

Status: Completed

Conditions: Polycystic Ovary Syndrome (PCOS)

Treatments: Other: 14 weeks exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT02429128

Lean PCOS & Training

Details and patient eligibility

About

The aim of this project is to investigate the pathophysiology of PCOS in regards to the metabolic profile including defects in insulin sensitivity in skeletal muscle and adipose tissue, and to investigate the effects of exercise training on these parameters.

Enrollment: 22 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: Women with PCOS

• Hyperandrogenism and/or hyperandrogenemia
• Regular menstruation
• Age: 20-40
• Inactive or low physical activity level
• Low to moderate fitness status

Inclusion Criteria: Women without PCOS

• Normal levels of plasma androgens
• Polycystic ovary and/or menstrual dysfunction
• Age: 20-40
• Inactive or low physical activity level
• Low to moderate fitness status

Exclusion Criteria: Women with and without PCOS

• Pregnancy or breast feeding
• Smoking
• Use of birth control pills 3 mo before enrolment

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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22 participants in 2 patient groups

Lean PCOS training

Active Comparator group

Description:

14 weeks exercise training

Treatment:

Other: 14 weeks exercise training

Lean healthy controls

Other group

Description:

14 weeks exercise training

Treatment:

Other: 14 weeks exercise training