18F-FAPI PET in Lung Cancer

Zhejiang University

Status: Not yet enrolling

Conditions: Lung Cancer (Diagnosis)

Treatments: Diagnostic Test: 18F-FAPI PET

Study type: Observational

Funder types: Other

Identifiers

NCT07370805

FirstZhejiangU-FAPI-Lung Ca

Details and patient eligibility

About

This study aims to evaluate the diagnostic efficacy and prognostic value of 18F-FAPI PET/CT in lung cancer.

Full description

1. Patients clinically suspected or confirmed with lung cancer are required to complete conventional imaging examinations (CT/MR or FDG PET) and undergo ¹⁸F-FAPI PET/CT.
2. Conduct a detailed inquiry into the patient's medical history to clarify symptoms, signs, and prior medical history (e.g., tumor history, surgical history, biopsy history, radiotherapy history, chemotherapy history, family history, allergy history, etc.), as well as relevant laboratory tests and previous imaging findings (including plain radiography, ultrasound, CT, MRI, 18F-FDG PET/CT, PET/MR, etc.).
3. For follow-up coordination, you are required to regularly provide your clinical data (e.g., treatment plans, disease progression, etc.) as per the study requirements. This collaboration is essential for completing long-term follow-up, including monitoring the subject's condition, imaging findings, pathological results (such as tumor grading and Ki-67 index), and patient treatment outcomes, to collect prognostic information.
4. ¹⁸F-FAPI PET/CT and conventional imaging examinations (e.g., CT/MR) were completed prior to enrollment. After enrollment in this study, subjects were not required to undergo additional imaging or laboratory tests, only requiring follow-up without intervention to the clinical treatment plan.

Enrollment: 120 estimated patients

Sex: All

Ages: 20 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Clinical diagnosis of Lung Cancer
2. With 18F FAPI PET scan

Exclusion criteria

1. Concurrent presence of other active malignant tumors or a history of other
2. malignant tumors within the past 5 years;
3. Severe uncontrollable diseases or active infections;
4. Ineligible participants for project informed consent；
5. Pregnant and lactating women.

Trial design

120 participants in 1 patient group

FAPI-Lung-ca

Description:

18F FAPI PET scans

Treatment:

Diagnostic Test: 18F-FAPI PET