18F-FDG PET/CT in Diagnostic Patients of Disorder of Consciousness

Guangzhou General Hospital of Guangzhou Military Command

Status: Completed

Conditions: Persistent Vegetative State

Treatments: Radiation: 18F-FDG

Study type: Interventional

Funder types: Other

Identifiers

NCT02999490

HYXK0001

Details and patient eligibility

About

Clinical examinations are difficult to discriminate between vegetative state and minimally conscious state. the diagnostic and prognostic usefulness of neuroimaging methods has not been established in a clinical setting. we will do a forward study of PET imaging in disorders of consciousness patients, and validate with clinical assessments with the coma recovery Scale-Revised(CRS-R).

Full description

Every patient need to be conducted the PET/CT scanning two times.The first time is resting state.The second time is stimulated state by watching a vedio.

Enrollment: 20 patients

Sex: All

Ages: 10 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of disorder of consciousness

Exclusion criteria

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20 participants in 2 patient groups

Controls

No Intervention group

Description:

The controls are intravenous injected of 185 to 370 MBq 18F-FDG.Then,the controls sleep for an hour in a quiet room before scanning.

Patients

Experimental group

Description:

The patients are intravenous injected of 185 to 370 MBq 18F-FDG.Then,the patients sleep for an hour in a quiet room before scanning.

Treatment:

Radiation: 18F-FDG