2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula

Mahidol University

Status and phase: Unknown; Phase 4

Conditions: Infraclavicular Brachial Plexus Block

Treatments: Drug: Bupivacaine plus lidocaine; Drug: Bupivacaine 30 ml

Study type: Interventional

Funder types: Other

Identifiers

NCT00993746

si433/2009

Details and patient eligibility

About

Will the technique of adding lidocaine to bupivacaine fasten the onset of bupivacaine alone for infraclavicular brachial plexus block in end-stage renal disease (ESRD) patient?

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ESRD patient for AVF procedure
• age >17 year
• BMI 20-35 kg/m2
• communicable

Exclusion criteria

• BMI > 35 kg/m2 BMI < 20 kg/m2 หรือ BW < 35 kg
• History of allergy to local anesthetic drugs
• Pre-operative neurological deficit, Neuromuscular disorder หรือ old CVA
• Psychiatric disorder
• Coagulation disorder
• Uncontrolled seizure
• Pregnant and lactating women

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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90 participants in 2 patient groups

Bupivacaine plus lidocaine

Active Comparator group

Description:

Group 1: bupivacaine 20 ml plus lidocaine 10 ml

Treatment:

Drug: Bupivacaine plus lidocaine

Bupivacaine alone

Experimental group

Description:

Group 2: bupivacaine 30 ml

Treatment:

Drug: Bupivacaine 30 ml