24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients

Aristotle University Of Thessaloniki

Status and phase: Completed; Phase 4

Conditions: Ocular Hypertension; Primary Open Angle Glaucoma

Treatments: Drug: latanoprost/timolol fixed combination; Drug: placebo (artificial tears); Drug: timolol maleate 0.5%

Study type: Interventional

Funder types: Other

Identifiers

NCT00330577

A594

Details and patient eligibility

About

The purpose of this study is to compare the short-term mean 24-hour intraocular pressure control, 24-hour blood pressure effect and safety of Latanoprost/Timolol fixed combination given once in the evening with placebo once in the morning versus timolol maleate 0.5% given twice daily in patients with ocular hypertension and primary open-angle glaucoma.

Sex: All

Ages: 29 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• POAG
• OHT

Exclusion criteria

• Advanced glaucoma
• Arterial Hypertension

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind