25-hydroxyvitamin D and Fatigue: The VITALITY Study

Ostfold Hospital Trust

Status: Completed

Conditions: Irritable Bowel Syndrome; Diabetes; Inflammatory Bowel Disease; Rheumatoid Arthritis

Study type: Observational

Funder types: Other

Identifiers

NCT01718925

3256

Details and patient eligibility

About

The burden of chronic disease is continuing to rise. Even though patients may be in remission or have quiescent disease, several studies have confirmed that symptoms, such as e.g., fatigue, is troublesome.

The primary aim of this study is to investigate whether or not there might be an association between levels of vitamin D and the subjective experience of fatigue in conditions, such as inflammatory bowel disease, diabetes mellitus, rheumatoid arthritis and irritable bowel syndrome.

Secondary aims is to study both the co-occurence and influence of pain, depression and anxiety.

Full description

The burden of chronic disease is continuing to rise. Even though patients may be in remission or have quiescent disease, several studies have confirmed that symptoms, such as e.g., fatigue, is troublesome.Previous studies have confirmed that vitamin D deficiency is associated with both Crohn's disease and Rheumatoid Arthritis. Since Vitamin D is associated with both onset of chronic disease and energy, we aim in this study to assess its impact on fatigue in various chronic diseases.

The primary aim of this study is to investigate whether or not there might be an association between levels of vitamin D and the subjective experience of fatigue in conditions, such as inflammatory bowel disease, diabetes mellitus, rheumatoid arthritis and irritable bowel syndrome.

Secondary aims is to study both the co-occurence and influence of pain, depression and anxiety.

Enrollment: 614 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• informed consent,
• over 18 years of age

Exclusion criteria

• dementia,
• cognitive disorders,
• not able to comply with the study procedures,
• on active vitamin D treatment

Trial design

614 participants in 4 patient groups

Inflammatory Bowel Disease

Description:

Ulcerative Colitis and Crohns's disease patients will be recruited from sqeduled outpatient follow-up

Irritable Bowel Syndrome

Description:

Irritable Bowel patients will be recruited from sqeduled outpatient follow-up

Rheumatoid Arthritis

Description:

Rheumatoid Arthritis patients will be recruited from sqeduled outpatient follow-up

Diabetes Mellitus

Description:

Diabetes mellitus patients will be recruited from sqeduled outpatient follow-up