2D and Tissue Doppler Imaging Echocardiography Analysis of Left Ventricular Regional Wall Motion and Prognosis (TDI)

Chang Gung Medical Foundation

Status: Unknown

Conditions: Coronary Artery Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01092429

96-1504B

Details and patient eligibility

About

Development of myocardial ischemia, and/or myocarditis would induce different changes in myocardial contraction behavior pattern,which maybe very subtle, and may not be detected by the 2D and m-mode echocardiography examinations. According to tissue Doppler imaging(TDI), they can be depicted by different models of echo with higher frame rates. In addition, many studies using TDI have significantly contributed of efforts to evaluate systolic and diastolic function and prognosis.

This study assess the value of the indices of left ventricular function obtained by using TDI in patient with coronary artery disease(CAD). We hypothesized that TDI will add incremental value for regional wall motion abnormality of CAD and its prognosis.

Enrollment: 500 estimated patients

Sex: All

Ages: 20 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Angina
2. Acue coronary syndrome
3. Left ventricular systolic dysfunction

Exclusion criteria

1. Significant valvular disease
2. Active cancer status
3. Acute Renal failure
4. Contrast allergy history
5. Pregnancy

Trial design

500 participants in 1 patient group

one,two,and three vessels disease; mortality