3 Airway Clearance Techniques in Non Cystic Fibrosis Bronchiectasis

Hospital Clinic of Barcelona

Status: Completed

Conditions: Bronchiectasis

Treatments: Other: Autogenic drainage; Other: Temporary-positive expiratory pressure; Other: Slow expiration with glottis opened in lateral posture

Study type: Interventional

Funder types: Other

Identifiers

NCT01854788

Uniko2010.01

Details and patient eligibility

About

Study design: a randomized, crossover trial. Each patient performed three different airway clearance techniques (Autogenic drainage, slow expiratory with glottis opened in lateral posture [ELTGOL], temporary- positive expiratory pressure [T-PEP] with not similar autonomy degree in a randomized order. Each technique were applied in 3 sessions during one week at alternate days (Monday /Wednesday/Friday or Tuesday/Thursday/Saturday). The time spent in each bronchial session was 40 minutes. Seven days were the wash-out time period between the different techniques.

Enrollment: 31 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. • Non Cystic Fibrosis bronchiectasis diagnosed by High Resolution Computed Tomographic
2. • Mean sputum production ≥ 15 ml /24h
3. • Clinical stability in the last 6 weeks
4. • Not carrying out regular chest physiotherapy
5. • Forced expiratory volume in 1 second ≥ 30% pred. ; Forced Vital Capacity ≥ 45% pred. and peak expiratory flow >270 L/s

Exclusion criteria

1. • Smoker or non-smoker form less than 2 years
2. • Cystic fibrosis
3. • Active tuberculosis or sarcoidosis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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31 participants in 3 patient groups

Autogenic drainage

Active Comparator group

Description:

All patients performed all interventions in a randomized order. Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes

Treatment:

Other: Autogenic drainage

Slow expiration with glottis opened in lateral posture

Active Comparator group

Description:

All patients performed all interventions in a randomized order.Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes

Treatment:

Other: Slow expiration with glottis opened in lateral posture

Temporary-Positive Expiratory Pressure

Active Comparator group

Description:

All patients performed all interventions in a randomized order. Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes

Treatment:

Other: Temporary-positive expiratory pressure