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3 Airway Clearance Techniques in Non Cystic Fibrosis Bronchiectasis

H

Hospital Clinic of Barcelona

Status

Completed

Conditions

Bronchiectasis

Treatments

Other: Autogenic drainage
Other: Temporary-positive expiratory pressure
Other: Slow expiration with glottis opened in lateral posture

Study type

Interventional

Funder types

Other

Identifiers

NCT01854788
Uniko2010.01

Details and patient eligibility

About

Study design: a randomized, crossover trial. Each patient performed three different airway clearance techniques (Autogenic drainage, slow expiratory with glottis opened in lateral posture [ELTGOL], temporary- positive expiratory pressure [T-PEP] with not similar autonomy degree in a randomized order. Each technique were applied in 3 sessions during one week at alternate days (Monday /Wednesday/Friday or Tuesday/Thursday/Saturday). The time spent in each bronchial session was 40 minutes. Seven days were the wash-out time period between the different techniques.

Enrollment

31 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

    • Non Cystic Fibrosis bronchiectasis diagnosed by High Resolution Computed Tomographic
    • Mean sputum production ≥ 15 ml /24h
    • Clinical stability in the last 6 weeks
    • Not carrying out regular chest physiotherapy
    • Forced expiratory volume in 1 second ≥ 30% pred. ; Forced Vital Capacity ≥ 45% pred. and peak expiratory flow >270 L/s

Exclusion criteria

    • Smoker or non-smoker form less than 2 years
    • Cystic fibrosis
    • Active tuberculosis or sarcoidosis

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

31 participants in 3 patient groups

Autogenic drainage
Active Comparator group
Description:
All patients performed all interventions in a randomized order. Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes
Treatment:
Other: Autogenic drainage
Slow expiration with glottis opened in lateral posture
Active Comparator group
Description:
All patients performed all interventions in a randomized order.Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes
Treatment:
Other: Slow expiration with glottis opened in lateral posture
Temporary-Positive Expiratory Pressure
Active Comparator group
Description:
All patients performed all interventions in a randomized order. Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes
Treatment:
Other: Temporary-positive expiratory pressure

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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