36 Versus 42 Hour Time Interval From Ovulation to Intrauterine Insemination

HaEmek Medical Center, Israel

Status: Terminated

Conditions: Infertility

Treatments: Procedure: Intrauterine Insemination 42 hours; Procedure: Intrauterine Insemination 36 hours

Study type: Interventional

Funder types: Other

Identifiers

NCT02210611

0038-14-EMC

Details and patient eligibility

About

The purpose of this study is to prove that a higher clinical pregnancy rate can be achieved with a 42 to 44 hour time interval between ovulation trigger and intrauterine insemination than a 36 to 38 hour time interval in stimulated cycles utilizing gonadotropins and GnRH antagonists.

Enrollment: 71 patients

Sex: Female

Ages: 17 to 44 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients who can be monitored for follicle growth and hormone measurements on the day of ovulation trigger, or one day before.
2. Patients who have no more than 4 follicles of 14 mm or more
3. Patients who have no more than 6 follicles of 10 mm or more

Exclusion criteria

1. Patients who cannot give informed consent to language or comprehension barriers
2. Patients who are deemed to be at high risk for high order multiple gestations
3. Patients who cannot be monitored on the day of hCG administration or one day before

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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71 participants in 2 patient groups

36 hours

Active Comparator group

Description:

Intrauterine insemination 36 hours after ovulation induction

Treatment:

Procedure: Intrauterine Insemination 36 hours

42 hours

Active Comparator group

Description:

Intrauterine insemination 42 hours after ovulation induction

Treatment:

Procedure: Intrauterine Insemination 42 hours