3D DL Ozteo in the Detection of Osseous Changes in Patients With Inflammatory Arthritis

Mayo Clinic

Status: Enrolling

Conditions: Inflammatory Arthritis

Treatments: Device: oZTEo

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT06383585

24-001367

Details and patient eligibility

About

This project intends to explore and validate the utility of new MRI pulse sequence, 3D DL oZTEo, in the detection of osseous erosions of the hand in patients with inflammatory arthritis. The detection of osseous structural changes, such as erosive disease, is routinely assessed in patients with rheumatic conditions such as rheumatoid arthritis, as it alters clinical management, and in some cases assists in diagnosis. Currently, this is most often assessed with radiography and conventional MRI.

Full description

This project intends to explore and validate the utility of new MRI pulse sequence, 3D DL oZTEo, in the detection of osseous erosions of the hand in patients with inflammatory arthritis.

Enrollment: 25 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients ≥18 years of age
• Hand radiographs performed within the past 3-6 months with imaging results available for analysis
• Hand radiographs confirm the presence of bony erosions
• Scheduled for a hand MRI as part of their routine clinical care at Mayo Clinic Rochester

Exclusion criteria

- Less than18 years of age

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

25 participants in 1 patient group

oZTEo MRI pulse sequence

Experimental group

Description:

All patients will have the FDA approved MRI pulse sequence, oZTEo, added to their already ordered standard of care MRI examination.

Treatment:

Device: oZTEo