ClinicalTrials.Veeva

Menu

3D Printed Bolus in Post-mastectomy Radiotherapy

J

Jiangxi Provincial Cancer Hospital

Status

Unknown

Conditions

Radiotherapy Side Effect
Breast Neoplasms

Treatments

Other: customized 3D-printed bolus fabricated based on reconstruction of computed tomography (CT) images

Study type

Interventional

Funder types

Other

Identifiers

NCT04685460
jcl2020-2 breast cancer

Details and patient eligibility

About

Recently, there is growing interest in the application of three-dimensional (3D) printed bolus to radiotherapy.At present, the researches on the application of 3D-printed bolus in breast cancer are mainly focused on air gap between skin and bolus or electron beam conformal therapy [7,15], there are no clinical experience with customized 3D-printed bolus for volumetric modulated arc therapy (VMAT) in daily practice has been published up to now. We aim to evaluate dosimetry and application of 3D-printed bolus for the post-mastectomy radiotherapy (PMRT) with Volumetric modulated arc therapy (VMAT). Seventy five patients with breast cancer receiving radiotherapy following post-mastectomy in our department were randomly selected in this study. The accuracy of fit of the 3D-Printed bolus to the chest wall was improved significantly relative to conventional bolus.This study demonstrates customized 3D-printed bolus in post-mastectomy radiation therapy improves fit of the bolus compared to conventional bolus. Furthermore, VMAT based on 3D-printed bolus significantly improves the chest wall target coverage and the conformity of plan, and reduces the dose of ipsilateral lung and heart, compared to conventional bolus.

Enrollment

70 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • breast cancer patients with post-mastectomy treatment

Exclusion criteria

  • NA

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

70 participants in 2 patient groups

3D-printed bolus
Experimental group
Treatment:
Other: customized 3D-printed bolus fabricated based on reconstruction of computed tomography (CT) images
Conventional bolus
No Intervention group

Trial contacts and locations

1

Loading...

Central trial contact

Chunling Jiang, Phd,MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems