3M Cavilon Advanced Skin Protectant for the Prophylaxis of Radiation Dermatitis

Mayo Clinic

Status

Completed

Conditions

Radiation Dermatitis

Treatments

Other: 3M™ Cavilon™ Advanced Skin Protectant

Study type

Observational

Funder types

Other

Identifiers

ROR1603 (Other Identifier)

17-006813

Details and patient eligibility

About

This study observes a liquid skin protectant that is a polymeric-cyanoacrylate solution designed to protect intact or damaged skin due to radiation.

Enrollment

14 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age ≥ 18years.
Patient has initial or recurrent disease
Undergoing external beam radiotherapy at the Mayo Clinic Rochester campus Note: Patients who are undergoing concurrent chemotherapy are eligible
Ability to complete questionnaire(s) by themselves or with assistance
Provide informed written consent
Willing to consent for photography of radiation field
Available to return to Mayo Clinic in within 1 week post treatment for assessment (+/- 7 days).
At risk for developing ≥ grade 2 dermatitis radiation as determined by treating Radiation Oncology clinician
Biologic effective dose of >42 Gy10 as calculated using the web site EQD2.com.

Exclusion criteria

Unable to provide informed consent
Patients with active rash, pre-existing dermatitis, lupus or scleroderma within the treatment area that may make skin assessment for the study difficult
Known history of developing an allergic reaction after using a product containing cyanoacrylate or acrylates
Subject has a medical condition that in the opinion of the investigator should exclude him/her from participating in the study
Subject has been enrolled in an investigational study where product was applied to the proposed study site within 30 days of the screening visit
The skin area affected by radiation requires treatment with a concomitant medication or product (if applicable)