4-10 Week Observational Study Comparing 3 Management Strategies for Obstructive Chronic BronchoPneumopathy (OCBP) in Common Clinical Practice (OBALPA)

Civil Hospices of Lyon

Status: Unknown

Conditions: Obstructive Chronic BronchoPneumopathy (OCBP)

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01885247

2012-746

Details and patient eligibility

About

The management of patients with Obstructive Chronic BronchoPneumopathy (OCBP) is based on a progression of therapeutic options and on a sensitization to physical activity.

For these patients selected on OCBP stage 2, the treatment options include Long Acting Beta-Agonist Bronchodilator (LABA) or Long Acting Muscarinic Antagonist Anticholinergic (LAMA) or both (LAMA+LABA).

The purpose of this study is to observe in common clinical practice the benefit of physical activity on quality of life, dyspnoea and walking distance for these patients under treatment (LABA and/or LAMA) and to determine whether these 3 medical strategies (LABA/LAMA/LABA+LAMA) benefit from physical activity.

Enrollment: 100 estimated patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with Obstructive Chronic BronchoPneumopathy stage ≥ 2.
• Patients under treatment with LABA or LAMA or LABA+LAMA since at least 1 month.
• VEMS/CVF<70%
• VEMS<80%
• Patients without regular physical activity and without physical activity program since 1 year.

Exclusion criteria

• Patients under treatment with LABA + inhaled Corticoids.
• Contraindication to physical activity.
• Patients with previous history of respiratory exacerbations.