400mcg Sublingual Misoprostol as First Line Treatment

Gynuity Health Projects

Status: Completed

Conditions: Incomplete Abortion

Treatments: Drug: Misoprostol

Study type: Interventional

Funder types: Other

Identifiers

NCT01939457

2.2.4

Details and patient eligibility

About

Women presenting with incomplete abortion and eligible for treatment with misoprostol were offered 400mcg sublingual misoprostol for treatment. Based on existing literature, the study hypothesises that women can successfully be treated with misoprostol alone as first line treatment.

Enrollment: 641 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• uterine size less than 12 weeks lmp
• open cervical os
• current or past vaginal bleeding
• willing to provide contact information for follow-up
• over 18 or with guardian consent

Exclusion criteria

• suspicion of ectopic pregnancy
• intrauterine device in place
• bad general health (infection, anemia, shoc)

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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641 participants in 1 patient group

misoprostol

Experimental group

Description:

400 mcg misoprostol sublingually

Treatment:

Drug: Misoprostol