4D-CT for Pancreatic Adenocarcinoma in Radiotherapy Simulation (GCC 1210)

University of Maryland Baltimore (UMB) logo

University of Maryland Baltimore (UMB)

Status

Completed

Conditions

Pancreatic Adenocarcinoma

Treatments

Other: Contrast-enhanced 4D computed tomography

Study type

Observational

Funder types

Other

Identifiers

NCT01764659
HP-00052534

Details and patient eligibility

About

The primary objective is to study the feasibility and efficacy of individually optimized CE 4D-CT for PDA in radiotherapy simulation.

Full description

Compared with current clinical practice, the individually optimized CE 4D-CT can potentially provide much improved tumor-to-parenchyma conspicuity of pancreatic adenocarcinoma. This will help the radiation oncologists or radiologists to contour the tumor with higher precision and confidence, and compute the tumor volume and tumor motion more accurately.

Enrollment

14 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Patients 18 years old or older
  2. Patients with PDA who have not had surgical removal of their tumor and who are planned for treatment with radiotherapy in the Radiation Oncology Department at the University of Maryland.
  3. Patients who have signed the contrast consent form and have been recommended by physicians to have contrast-enhanced CT scans.
  4. Patients who have signed the consent form for this study

Exclusion criteria

  1. Pregnant or breast-feeding women.
  2. Patients with severely decreased renal function19-21.
  3. Patients with known severe allergic reactions to contrast.
  4. Patients who have difficulty lying flat on their back for extended periods of time.
  5. Patients with breaths per minute (BPM) rate less than 10, due to the limitation of 4D-CT image reconstruction software.

Trial design

14 participants in 1 patient group

All enrolled patients
Description:
Contrast-enhanced 4D computed tomography
Treatment:
Other: Contrast-enhanced 4D computed tomography

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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