4D Medical X-ray Velocimetry for Bronchoscopic Lung Volume Reduction Targeting

Vanderbilt University Medical Center

Status: Completed

Conditions: Hyperinflation; Emphysema; Copd

Treatments: Diagnostic Test: 4D X-ray Velocimetry

Study type: Observational

Funder types: Other

Identifiers

NCT04786171

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Details and patient eligibility

About

This study will investigate the utility of 4D Medical's X-ray Velocimetry (XV) imaging analysis software for the detection of hyperinflation, and compare endobronchial valve placement outcomes with predictive indices obtained utilizing this technique.

Enrollment: 17 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion:

• CT chest and PFTs within the last two years
• Age over 18
• COPD with emphysema
• Global Initiative for Chronic Obstructive Lung Disease (GOLD) 3 - 4 classification OR modified Medical Research Council (mMRC) score of 2 or greater.

Exclusion Criteria:

• Pregnancy
• Presence of an additional pulmonary disease beyond COPD
• Inability to raise arms above 90 degrees as required for fluoroscopy