5 Year Registry Study to Track Clinical Application of DecisionDx-UM Assay Results and Associated Patient Outcomes (CLEAR)

Castle Biosciences

Status: Completed

Conditions: Uveal Melanoma

Study type: Observational

Funder types: Industry

Identifiers

NCT02376920

2-01

Details and patient eligibility

About

Uveal Melanoma is a rare cancer with approximately 3,000 cases diagnosed in the US every year. Nearly half of these experience spread of their cancer outside the eye. The DecisionDx-UM gene expression test classifies an individual's tumor as low risk (class 1) or high risk (class 2) of spreading. This study is being done to collect information about how physicians are using the DecisionDx-UM results to design individual treatment plans. It will also track outcomes or the uveal melanoma population that received DecisionDx-UM testing.

Enrollment: 93 patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with a diagnosis of Uveal Melanoma
• Patients whose physician deems them appropriate for DecisionDx-UM testing
• Patients reasonably able to follow up with enrolling physician at regular intervals for assessment of outcome data

Exclusion criteria

• Patients with any other form of cancer