7T MRI to Evaluate Cartilage Defects in the Knee

The Methodist Hospital Research Institute (TMHRI)

Status: Completed

Conditions: Knee Pain Swelling; Knee Injuries; Cartilage Injury; Cartilage Damage; Arthropathy of Knee

Treatments: Diagnostic Test: 7 Tesla Magnetic Resonance Imaging Test

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT04118023

Pro00022554

Details and patient eligibility

About

The investigators propose to prospectively evaluate the accuracy of a novel 7-Tesla (7T) knee MRI protocol for the detection and grading of cartilage lesions in the knee, which is a significant limitation of current MRI techniques.

Full description

The investigators hypothesize that 7T MRI will be ~ 80% sensitive for detection of cartilaginous lesions. This will be tested in a prospective multi-reader study of 100 patients who are scheduled to have knee arthroscopy. Patients will have two MRIs of the knee: one standard of care and one experimental 7T MRI. Subjects will visit at one time point prior to scheduled knee arthroscopy, for a session time of ~1-2 hours for a single 7T MRI scan.

Enrollment: 112 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed Knee Symptomatology
• Scheduled Arthroscopic Treatment of Knee
• Adult (equal or greater than 18 years of age)

Exclusion criteria

• Active infections
• Less than 18 years of age
• Pregnant

Trial design

112 participants in 1 patient group

7T MRI Group

Description:

Patient group that receives 7 Tesla Magnetic Resonance Imaging

Treatment:

Diagnostic Test: 7 Tesla Magnetic Resonance Imaging Test