A Bilateral Interconnected DIEP Flap Based on One Vessel Pedicle for Breast Reconstruction

Chinese Academy of Sciences

Status: Completed

Conditions: Mammaplasty

Treatments: Procedure: DIEP; Procedure: Interconnected DIEP

Study type: Interventional

Funder types: Other

Identifiers

NCT00514748

621125-2

Details and patient eligibility

About

Bilateral DIEP flap needs two groups of vessel pedicles. We suppose that the bilateral DIEP flap may survive on one vessel pedicle by means of interconnection of bilateral DIEA. This study is aimed to build a interconnected vessel system of bilateral DIEP flap based on one vessel pedicle and observe its survival in breast reconstruction.

Full description

The DIEP flap have become the most common and primary choice in autogenous tissue breast reconstruction nowadays. In cases with inadequate abdominal soft-tissue volume or abdominal midline scar, the bilateral DIEP flap is needed.However, it need two groups of recipient vessels. So it is unavailable in cases short of two groups of recipient vessels after radiotherapy. This study is aimed to solve the problems by interconnecting one of the branches of DIEA each side. The MDCT will be used to predict the branches and perforators of DIEA both sides. According to the branches of DIEAs, one branch will be anastomosed with that on contralateral side with only one vessel pedicle preserved on one side. We believe that the whole flap can be completely nourished with only one vessel pedicle by means of vessel interconnection.

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Breast lost after mastectomy
• With good general condition
• No pregnancy demand
• With additional soft tissue needed for reconstruction

Exclusion criteria

• With bad general condition
• DIEA damaged by previous surgery
• Limited abdominal tissue

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

1

Active Comparator group

Description:

Patients who receive breast reconstruction with bilateral DIEP flap based on bilateral vessel pedicles

Treatment:

Procedure: DIEP

2

Experimental group

Description:

Patient who receive breast reconstruction with vessel interconnected DIEP flap based on one vessel pedicle

Treatment:

Procedure: Interconnected DIEP