A Biomarker for Personalized Care in Post-Stroke Spatial Neglect

VA Office of Research and Development

Status: Active, not recruiting

Conditions: Spatial Neglect; Stroke

Study type: Observational

Funder types: Other U.S. Federal agency

Identifiers

NCT05256563

N3760-P

Details and patient eligibility

About

More than 30,000 Veterans are hospitalized for stroke each year, and in the critical first months of recovery, at least half are disabled by abnormal 3-D spatial function (spatial neglect). Their self-care, mobility, and ability to return home are severely limited.

Full description

Spatial Neglect (SN)is an underdiagnosed stroke-related condition--and a specific core set of symptoms--Aiming Spatial Neglect-- may have a major adverse effect on outcome. These same symptoms may predict excellent response to spatial neglect therapy. The investigators seek to develop a biological parameter for treatment assignment. In this two-year study, the investigators will enroll 45 people with right brain stroke who are at high risk of SN. The investigators will examine clinical brain images, behavioral assessment and research brain images at baseline and recovery at 3 and 6 months after study entry.

Enrollment: 45 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Stroke survivors >18 years
• 1-8 months post-stroke
• Can undergo testing and give informed consent

Exclusion criteria

• Other serious
• Chronic neurological disorders
• Evidence of other serious strokes
• Inability to undergo testing or give informed consent

Trial design

45 participants in 1 patient group

Right brain stroke survivors

Description:

People with right brain stroke who are recruited to the study.