A Botanical Skin Care Regimen on Mild to Moderate Acne and the Microbiome

Integrative Skin Science and Research

Status: Unknown

Conditions: Acne Vulgaris

Treatments: Other: Multi-Step Botanical Skin Care Regimen

Study type: Interventional

Funder types: Industry; Other

Identifiers

NCT05271487

CB_Acne_01

Details and patient eligibility

About

The purpose of this study is to analyze changes in acne and changes in the gut and skin microbiome with the use of a multi-step botanical skin care regimen in those with mild to moderate acne.

Enrollment: 20 estimated patients

Sex: All

Ages: 15 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subjects 15 years of age until 45 years of age.
• The presence of mild to moderate acne based on investigator global assessment.

Exclusion criteria

• The presence of severe acne as noted by the investigator global assessment.
• Those with a nut allergy.
• Those who are unwilling to discontinue oral probiotic-based supplementation to meet the washout criteria prior to enrolling.
• Those who are unwilling to discontinue topical antibiotics and topical benzoyl peroxide to meet the washout criteria prior to enrolling.
• Individuals who are unwilling to discontinue vitamin E containing supplements during the washout and intervention.
• Individuals who have been on an oral antibiotic for acne within the previous 1 month.
• Individuals who are pregnant or breastfeeding.
• Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
• Oral supplementation that has nuts in it.
• Use of isotretinoin within the three months prior to joining the study.
• Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Multi-Step Botanical Skin Care Regimen

Experimental group

Description:

The patient will be provided with and instructed to use a cleanser, toner, oil control cream, exfoliating facial scrub, clay mask, acne spot treatment, and body scrub for the duration of the study.

Treatment:

Other: Multi-Step Botanical Skin Care Regimen