A Capsular Incision and Biochemical Recurrence After Radical Perineal Prostatectomy
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To evaluate the impact of capsular incisions on biochemical recurrence (BCR) and the potential risk factors of capsular incisions.
Full description
The pathological classification of the prostate following radical prostatectomy provides important prognostic information; an accurate pathology report is the cornerstone to cancer treatment and follow-up. In addition to the preoperative serum PSA, Gleason score on pathology specimens, seminal vesicle invasion and lymph node status, and a positive surgical margin with extraprostatic extension (EPE) are significant predictors of clinical and biochemical recurrence. However, the prognostic implication of a capsular incision, a tumor extending to the inked margins without a histologically documented EPE, remains to be defined.
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Inclusion criteria
- pathologically proven prostate cancer
- follow-up for at least 6 months
Exclusion criteria
- insufficient biopsy data
- seminal vesicle invasion or lymph node involvement on pathology
- neoadjuvant or adjuvant therapy
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Data sourced from clinicaltrials.gov
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