A Case-control Study of Costa Rican Adults With Myocardial Infarction

University of Michigan

Status: Completed

Conditions: Myocardial Infarction, Acute

Study type: Observational

Funder types: Other

Identifiers

NCT03308838

HUM00037337

Details and patient eligibility

About

This observational case-control trial sought to identify and characterize different exposures associated with nonfatal acute myocardial infarction in Costa Rican adults. Exposures assessed included dietary variables and adipose tissue fatty acids.

Enrollment: 4,547 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Cases were eligible if they met the World Health Organization criteria for MI

Exclusion Criteria (Cases):

• Died during hospitalization
• Were 75 years or older on the day of their first MI
• Were physically or mentally unable to answer the questionnaire
• Had a previous hospital admission related to cardiovascular disease

Exclusion Criteria (Controls):

• Ever had an MI
• Were physically or mentally unable to answer the questionnaire

Trial design

4,547 participants in 2 patient groups

Cases

Description:

Cases consisted of Costa Rican adults who were diagnosed as survivors of a first acute myocardial infarction.

Controls

Description:

Controls consisted of healthy individuals randomly identified from the underlying source population in Costa Rica and matched to each case by age, sex, and area of residence.