A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients (ADFICE_IT)

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Status: Enrolling

Conditions: Fall Injury; Polypharmacy; Aged, 80 and Over; Accidental Fall; Aged; Fall Patients; Fall; Deprescriptions

Treatments: Device: CDSS; Device: Patient Portal

Study type: Interventional

Funder types: Other

Identifiers

NCT05449470

2021_061

Details and patient eligibility

About

Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls. Research indicates fall-risk increasing drug (FRID) deprescribing is effective in reducing falls but difficult to initiate and to sustain over longer periods of follow-up. A clinical decision support system (CDSS) and patient portal for communicating medication-related fall risk to fall clinic patients may improve joint medication management between patients and physicians and consequently reduce the incidence of injurious falls.

Full description

This study investigates the effectiveness and cost-effectiveness of the concurrent use of a CDSS and a patient portal for personalized FRID deprescribing, and will be assessed through a multicenter cluster-randomized controlled trial among new fall clinic patients, aged 65 years or older. The main study parameter is the time to first injurious fall. The primary objective of the ADFICE_IT study is to investigate the effects of a CDSS and accompanying patient portal for optimizing FRID deprescribing on injurious falls. This study has three secondary objectives. First, the effect of the CDSS and patient portal on a number of secondary outcomes will be investigated. Second, a process evaluation to evaluate the implementation of the CDSS and patient portal will be conducted. Third, the cost-effectiveness of the CDSS and patient portal will be investigated.

Enrollment: 800 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• History of at least one fall in the past year;
• A Mini-Mental State Examination (MMSE) score of 21 points or higher or equivalently a Montreal Cognitive Assessment (MOCA) Dutch score of 16 points or higher;
• Use of at least one fall-risk increasing drug (FRID); and
• Sufficient command of the Dutch language in speech and writing.

Exclusion criteria

• Active participation in another study;
• Life expectancy of less than one year: and/or
• Suffering from severe mobility impairment (i.e. bedridden, e.g. inability to walk short distances with assistance of a walking aid).

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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800 participants in 2 patient groups

CDSS and patient portal

Experimental group

Description:

The intervention includes the combined use of the clinical decision support system (CDSS) that provides deprescribing advice and a personalized risk prediction and a patient portal.

Treatment:

Device: Patient Portal

Device: CDSS

Care as usual

No Intervention group

Description:

Care as usual