A Clinical Model for Dialysis Discontinuation in AKI

University of Sao Paulo General Hospital

Status: Completed

Conditions: Acute Kidney Injury; Acute Renal Failure

Study type: Observational

Funder types: Other

Identifiers

NCT06005896

51678521.0.0000.0068

Details and patient eligibility

About

A retrospective study evaluating AKI patients in whom RRT was interrupted for at least 48 hours. Patients who were still RRT-independent 7 days after initial RRT cessation were included in the "Success" group, as opposed to the "Failure" group. Baseline characteristics and variables at the time of RRT interruption were collected. Multivariable analysis was performed and a model was generated to evaluate the prediction of success.

Enrollment: 124 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients receiving kidney replacement therapy due to AKI from October 2020 to February 2022 were considered for inclusion in the study. Patients who managed to remain at least 48 consecutive hours without receiving kidney replacement therapy prescription were included.

Exclusion criteria

• Patients who had kidney replacement therapy interrupted exclusively due to haemodynamic instability, death or decision for palliative care were excluded.

Trial design

124 participants in 2 patient groups

Success

Description:

Patients who were alive and free from RRT 7 days after interrupting RRT.

Failure

Description:

Patients who were not alive or who needed to dialyse again after interrupting RRT for at least 48h.