A Clinical Study of Hyperthyroidism in Children

China Medical University

Status: Enrolling

Conditions: Hyperthyroidism

Treatments: Drug: Methimazole(MMI)

Study type: Observational

Funder types: Other

Identifiers

NCT06570967

1223

Details and patient eligibility

About

This study intends to conduct a retrospective and prospective study on children with hyperthyroidism, and it is a non-intervention study to collect information on diagnosis and treatment and long-term follow-up of children with hyperthyroidism. To investigate the clinical characteristics, treatment effect, side effects and remission of hyperthyroidism in children, to analyze the predictive factors for the effect of antithyroid drug treatment, remission and recurrence after drug withdrawal, and to explore the risk factors related to the occurrence of antithyroid drug-related adverse reactions.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 29 days to 14 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age ≤14 years old
2. Initial diagnosis of hyperthyroidism

Exclusion criteria

1. Hyperthyroidism had been treated with medication in other hospitals,
2. History of autoimmune hepatitis, viral hepatitis, hematological diseases, bone marrow or liver transplantation,
3. Patients with incomplete clinical data

Trial design