A Clinical Study of the Effects of Environmental Pollution on Obesity

Dong Peng

Status: Active, not recruiting

Conditions: Obesity and Overweight

Treatments: Diagnostic Test: Obesity

Study type: Observational

Funder types: Other

Identifiers

NCT06670703

ZZ2024-350-02

Details and patient eligibility

About

This study aims to assess the effects of environmental pollution (including environmental indicators such as PM2.5, PM5, PM10, SO2, NOX, O3, and greening index) on obese patients and to explore the possible mechanisms by which environmental pollution promotes obesity.

Full description

Firstly, the effects of environmental pollution on obese patients were investigated by analysing the baseline conditions and obesity levels (including BMI, waist circumference, hip circumference, etc.) and underlying diseases of obese patients in regions with different pollution levels. Secondly, the association between environmental pollution levels on blood test characteristics (including renal function, sex hormones, glucose tolerance test, trace elements, liver function and blood routine) of obese patients was investigated to find possible mechanisms.

Enrollment: 800 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years;
• obese patients with BMI ≥30;
• patients without surgical treatment prior to enrolment;
• willingness to participate in the study and sign an informed consent form;
• complete clinical data.

Exclusion criteria

• patients with systemic diseases such as severe cardiorespiratory insufficiency affecting the choice of treatment regimen;
• patients assessed by the investigator to be inappropriate for enrolment;
• patients with incomplete clinical data.

Trial design

800 participants in 1 patient group

the obesity group

Description:

Obese patients attending the First Affiliated Hospital of Chongqing Medical University, the Affiliated Hospital of Yunnan University, and the Second People's Hospital of Qujing City.

Treatment:

Diagnostic Test: Obesity